Prognostic Value of Simplified Clinical Pulmonary Infection Score in Patients with Ventilator-associated Pneumonia_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

 ZhangMin , YeXiaoling , JinJinlan , ZhangRui , ChaoShuren

Intensive Care Unit, Guangzhou Red Cross Hospital, Jinan University, Guangzhou, Guangdong, 510220, China;

Corresponding author：

ZhangMin, Email: zhangmincc@163.com

Keywords：

Ventilator-associated pneumonia; Prognosis; Simplified clinical pulmonary infection score

DOI：

10.7507/1671-6205.2014092

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective To assess the value of simplified clinical pulmonary infection score (sCPIS) in predicting prognosis of patients with ventilator-associated pneumonia (VAP). Methods The clinical data of 52 patients with VAP,admitted in ICU between January 2011 and December 2012,were retrospectively analyzed. The sCPIS was calculated at the onset,and on 3^rd,5^th and 7^th day after onset of VAP. Results 24 cases survived and 28 cases died in 28-day's hospitalization. 28-day mortality was 53.8%. A significant decrease in sCPIS scores was found on 3^rd,5^th and 7^th day after onset compared with at the onset of VAP in the survivors(4.8±1.2,4.0±1.1,3.3±1.6 vs. 5.5±1.4,P<0.05). An increase in sCPIS scores was found on 3^rd,5^th and 7^th days after onset compared with at the onset of VAP in the non-survivors (6.8±1.3,7.5±1.4,7.8±1.2 vs. 5.8±1.5,P<0.05). The sCPIS determined at the time of VAP diagnosis and on 3^rd,5^th and 7^th day after onset was significantly higher in the non-survivors than that in the survivors respectively (P<0.05). The duration of mechanical ventilation and the length of ICU stay were longer in the non-survivors than those in the survivors[(18.4±5.2) d vs. (12.0±4.1) d,(22.5±8.5) d vs. (16±6.3) d,P<0.05]. Conclusion Serial measurement of sCPIS is valuable in evaluating the severity of illness and predicting the prognosis.

Citation： ZhangMin, YeXiaoling, JinJinlan, ZhangRui, ChaoShuren. Prognostic Value of Simplified Clinical Pulmonary Infection Score in Patients with Ventilator-associated Pneumonia. Chinese Journal of Respiratory and Critical Care Medicine, 2014, 13(4): 378-380. doi: 10.7507/1671-6205.2014092 Copy

1.	Pugin J,Auckenthaler R,Mili N,et al.Diagnosis of ventilator-associated pneumonia by bacteriologic analysis of bronchoscopic and non bronchoscopic "blind" bronchoalveolar lavage fluid.Am Rev Respir Dis,1991,143:1121-1129.
2.	Luna CM,Blanzaco D,Niederman MS,et al.Resolution of ventilator-associated pneumonia:prospective evaluation of the clinical pulmonary infection score as an early clinical predictor of outcome.Crit Care Med,2003,31:676-682.
3.	Nseir S,Marquette CH.Diagnosis of hospital-acquired pneumonia:postmortem studies.Infect Dis Clin North Am,2003,17:707-716.
4.	American Thoracic Society,Infectious Diseases Society of America.Guidelines for the management of adults with hospital-acquired,ventilator-associated,and healthcare-associated pneumonia.Am J Respir Crit Care Med,2005,171:388-416.
5.	杨国辉,王广发.临床肺部感染评分对呼吸机相关肺炎患者预后的评价.中华结核和呼吸杂志,2006,29:751-754.
6.	卢健聪,蔡绍曦,耿穗娜,等.耐碳青霉烯鲍曼不动杆菌医院获得性肺炎的危险因素及预后分析.中国呼吸与危重监护杂志,2009,8:24-27.
7.	Singh N,Rogers P,Atwood CW,et al.Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit.A proposed solution for indiscriminate antibiotic prescription.Am J Respir Crit Car Med,2000,162:505-511.

1. Pugin J,Auckenthaler R,Mili N,et al.Diagnosis of ventilator-associated pneumonia by bacteriologic analysis of bronchoscopic and non bronchoscopic "blind" bronchoalveolar lavage fluid.Am Rev Respir Dis,1991,143:1121-1129.
2. Luna CM,Blanzaco D,Niederman MS,et al.Resolution of ventilator-associated pneumonia:prospective evaluation of the clinical pulmonary infection score as an early clinical predictor of outcome.Crit Care Med,2003,31:676-682.
3. Nseir S,Marquette CH.Diagnosis of hospital-acquired pneumonia:postmortem studies.Infect Dis Clin North Am,2003,17:707-716.
4. American Thoracic Society,Infectious Diseases Society of America.Guidelines for the management of adults with hospital-acquired,ventilator-associated,and healthcare-associated pneumonia.Am J Respir Crit Care Med,2005,171:388-416.
5. 杨国辉,王广发.临床肺部感染评分对呼吸机相关肺炎患者预后的评价.中华结核和呼吸杂志,2006,29:751-754.
6. 卢健聪,蔡绍曦,耿穗娜,等.耐碳青霉烯鲍曼不动杆菌医院获得性肺炎的危险因素及预后分析.中国呼吸与危重监护杂志,2009,8:24-27.
7. Singh N,Rogers P,Atwood CW,et al.Short-course empiric antibiotic therapy for patients with pulmonary infiltrates in the intensive care unit.A proposed solution for indiscriminate antibiotic prescription.Am J Respir Crit Car Med,2000,162:505-511.

Chinese Journal of Respiratory and Critical Care Medicine

Prognostic Value of Simplified Clinical Pulmonary Infection Score in Patients with Ventilator-associated Pneumonia

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content