One Year's Follow-up of Home Mechanical Ventilation for Stable Chronic Obstructive Pulmonary Disease Patients with Respiratory Failure_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

 WangJinxiang , DingLin , ZhangXin , ZhangChunmei , LinRuiyan , ZhangHongxia , XuZhenyang

Department of Respiratory and Critical Care Medicine, Luhe Teaching Hospital of Capital Medical University, Beijing, 101149, China;

Corresponding author：

WangJinxiang, Email: wangjx0090@sina.com

Keywords：

Chronic obstructive pulmonary disease; Respiratory failure; Home mechanical ventilation; Non-invasive positive pressure ventilation

DOI：

10.7507/1671-6205.2014136

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective To evaluate the effects of home mechanical ventilation (HMV) for stable chronic obstructive pulmonary disease (COPD) patients with respiratory failure in Tongzhou district of Beijing city. Methods Twenty stable COPD patients with respiratory failure were included in the study.During the one-year follow-up period,4 patients died and 1 withdrew and 15 patients finished the follow-up.The patients was followed up by telephone each month and guided in drug administration,HMV,and rehabilitation therapy.At the beginning of the study and one year later,the patients were interviewed and accessed on the general data,nutritional status,COPD assessment test (CAT),Borg dyspnea and respiratory fatigue score,Hamilton depression scale,Hamilton anxiety scale,and arterial blood gas analysis. Results At the end of one-year follow-up,nutrition index,CAT,Borg dyspnea and respiratory fatigue score,Hamilton depression scale,Hamilton anxiety scale,pH,and PaO₂ did not change significantly (P>0.05),while PaCO₂ decreased significantly compared with those at the beginning of the study (P<0.05).Compared with the past year,the times of hospitalization due to acute exacerbation of COPD was significantly reduced during the follow-up year (P<0.05). Conclusion HMV can ameliorate carbon dioxide retention and reduce times of hospitalization due to acute exacerbation of COPD for COPD patients with respiratory failure.

Citation： WangJinxiang, DingLin, ZhangXin, ZhangChunmei, LinRuiyan, ZhangHongxia, XuZhenyang. One Year's Follow-up of Home Mechanical Ventilation for Stable Chronic Obstructive Pulmonary Disease Patients with Respiratory Failure. Chinese Journal of Respiratory and Critical Care Medicine, 2014, 13(6): 556-559. doi: 10.7507/1671-6205.2014136 Copy

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4.	王金祥,张虹霞,胥振阳,等.无创正压通气对慢性阻塞性肺疾病急性加重并不同程度二氧化碳潴留患者治疗效应的对比分析.临床肺科杂志,2011,16:1352-1354.
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7.	Casanova C,Celli BR,Tost L,et al.Long-term controlled trial of nocturnal nasal positive pressure ventilation in patients with severe COPD.Chest,2000,118:1582-1590.
8.	Clini E,Sturani C,Rossi A,et al.The Italian multicentre study on noninvasive ventilation in chronic obstructive pulmonary disease patients.Eur Respir J,2002,20:529-538.
9.	McEvoy RD,Pierce RJ,Hillman D,et al.Nocturnal noninvasive nasal ventilation in stable hypercapnic COPD:a randomized controlled trial.Thorax,2009,64:561-566.
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11.	Diaz O,Begin P,Andresen M,et al.Physiological and clinical effects of diurnal noninvasive ventilation in hypercapnic COPD.Eur Respir J,2005,26:1016-1023.
12.	Gay PC,Hubmayr RD,Stroetz RW.Efficacy of nocturnal nasal ventilation in stable,severe chronic obstructive pulmonary disease during a 3-month controlled trial.Mayo Clin Proc,1996,71:533-542.
13.	Sin DD,Wong E,Mayers I,et al.Effects of nocturnal noninvasive mechanical ventilation on heart rate variability of patients with advanced COPD.Chest,2007,131:156-163.
14.	Diaz O,Begin P,Torrealba B,et al.Effects of noninvasive ventilation on lung hyperinflation in stable hypercapnic COPD.Eur Respir J,2002,20:1490-1498.
15.	Robert D,Gérard M,Leger P,et al.Ventilation mecanique a domicile des insuffisants respiratoires chroniques.Rev Fr Mai Resp,1983,11:923-936.
16.	Dreher M,Storre H,Schmoor C,et al.High-intensity versus low-intensity non-invasive ventilation in patients with stable hypercapnic COPD:a randomized crossover trial.Thorax,2010,65:303-308.
17.	Windisch W,Haenel M,Storre JH,et al.High-intensity noninvasive positive pressure ventilation for stable hypercapnic COPD.Int J Med Sci,2009,6:72-76.

1. Leger P,Bedicam JM,Cornette A,et al.Nasal intermittent positive pressure.Long-term follow-up in patients with severe chronic respiratory insufficiency.Chest,1994,105:100-105.
2. Mehta S,Hill NS.Noninvasive ventilation.Am J Respir Crit Care Med,2001,163:540-577.
3. Nauffal D,Doménech R,Martínez García MA,et al.Noninvasive positive pressure home ventilation in restrictive disorders:outcome and impact on health-related quality of life.Respir Med,2002,96:777-783.
4. 王金祥,张虹霞,胥振阳,等.无创正压通气对慢性阻塞性肺疾病急性加重并不同程度二氧化碳潴留患者治疗效应的对比分析.临床肺科杂志,2011,16:1352-1354.
5. Nutrition screening initiative.Nutrition screening manual for professional caring for older Americans.Washington DC:Nutrition screening initiative,1991.
6. 向平超,张鑫,杨珺楠,等.家庭无创正压机械通气对稳定期重度慢性阻塞性肺疾病患者的疗效和安全性观察.中华结核和呼吸杂志,2007,30:746-757.
7. Casanova C,Celli BR,Tost L,et al.Long-term controlled trial of nocturnal nasal positive pressure ventilation in patients with severe COPD.Chest,2000,118:1582-1590.
8. Clini E,Sturani C,Rossi A,et al.The Italian multicentre study on noninvasive ventilation in chronic obstructive pulmonary disease patients.Eur Respir J,2002,20:529-538.
9. McEvoy RD,Pierce RJ,Hillman D,et al.Nocturnal noninvasive nasal ventilation in stable hypercapnic COPD:a randomized controlled trial.Thorax,2009,64:561-566.
10. Renston JP,DiMarco AF,Supinski GS.Respiratory muscle rest using nasal BiPAP ventilation in patients with stable severe COPD.Chest,1994,105:1053-1060.
11. Diaz O,Begin P,Andresen M,et al.Physiological and clinical effects of diurnal noninvasive ventilation in hypercapnic COPD.Eur Respir J,2005,26:1016-1023.
12. Gay PC,Hubmayr RD,Stroetz RW.Efficacy of nocturnal nasal ventilation in stable,severe chronic obstructive pulmonary disease during a 3-month controlled trial.Mayo Clin Proc,1996,71:533-542.
13. Sin DD,Wong E,Mayers I,et al.Effects of nocturnal noninvasive mechanical ventilation on heart rate variability of patients with advanced COPD.Chest,2007,131:156-163.
14. Diaz O,Begin P,Torrealba B,et al.Effects of noninvasive ventilation on lung hyperinflation in stable hypercapnic COPD.Eur Respir J,2002,20:1490-1498.
15. Robert D,Gérard M,Leger P,et al.Ventilation mecanique a domicile des insuffisants respiratoires chroniques.Rev Fr Mai Resp,1983,11:923-936.
16. Dreher M,Storre H,Schmoor C,et al.High-intensity versus low-intensity non-invasive ventilation in patients with stable hypercapnic COPD:a randomized crossover trial.Thorax,2010,65:303-308.
17. Windisch W,Haenel M,Storre JH,et al.High-intensity noninvasive positive pressure ventilation for stable hypercapnic COPD.Int J Med Sci,2009,6:72-76.

Chinese Journal of Respiratory and Critical Care Medicine

One Year's Follow-up of Home Mechanical Ventilation for Stable Chronic Obstructive Pulmonary Disease Patients with Respiratory Failure

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