Citation: 张凌, 李庆云. 睡眠呼吸暂停生物学标志物的研究进展. Chinese Journal of Respiratory and Critical Care Medicine, 2015, 14(1): 117-123. doi: 10.7507/1671-6205.2015031 Copy
1. | Young T, Palm M, Dempsey J, et al.The occurrence of sleep-disordered breathing among middle-aged adults.N Engl J Med, 1993, 328:1230-1235. |
2. | 高维杰, 王彦, 孙玫, 等.持续气道正压通气治疗阻塞性睡眠呼吸暂停低通气综合征的依从性调查.中华结核和呼吸杂志, 2011, 34:68-69. |
3. | Krieger J.Long-term compliance with nasal continuous positive airway pressure (CPAP) in obstructive sleep apnea patients and nonapneic snorers.Sleep, 1992, 15(6 Suppl):S42-S46. |
4. | Sanders MH, Gruendl CA, Rogers RM.Patient compliance with nasal CPAP therapy for sleep apnea.Chest, 1986, 90:330-333. |
5. | Weaver TE, Kribbs NB, Pack AI, et al.Night-to-night variability in CPAP use over first three months of treatment.Sleep, 1997, 20:278-283. |
6. | 孙士波, 郝青林, 徐鸥, 等.长期自动调节压力持续正压通气治疗阻塞性睡眠呼吸暂停低通气综合征的临床观察.国际呼吸杂志, 2012, 32:201-203. |
7. | 李庆云.慢性间歇低氧与氧化应激.中华结核和呼吸杂志, 2009, 32:646-647. |
8. | 郭雪玲, 刘辉国.慢性间歇低氧血管内皮功能障碍与氧化应激的关系研究进展.中华结核和呼吸杂志, 2012, 35:203-206. |
9. | Simiakakis M, Kapsimalis F, Chaligiannis E, et al.Lack of effect of sleep apnea on oxidative stress in obstructive sleep apnea syndrome (OSAHS) patients.PLoS ONE, 2012, 7:e39172. |
10. | Carpagnano GE, Kharitonov SA, Resta O, et al.Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients.Chest, 2002, 122:1162-1167. |
11. | Carpagnano GE, Kharitonov SA, Resta O, et al.8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy.Chest, 2003, 124:1386-1392. |
12. | Weiss JW, Liu Y, Li X, et al.Nitric oxide and obstructive sleep apnea. Respir Physiol Neurobiol, 2012, 184:192-196. |
13. | Ip MS, Lam B, Chan LY, et al.Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure.Am J Respir Crit Care Med, 2000, 162:2166-2171. |
14. | Alonso-Fernández A, García-Río F, Arias MA, et al.Effects of CPAP on oxidative stress and nitrate efficiency in sleep apnoea:a randomized trial.Thorax, 2009, 64:581-586. |
15. | Del Ben M, Fabiani M, Loffredo L, et al.Oxidative stress mediated arterial dysfunction in patients with obstructive sleep apnoea and the effect of continuous positive airway pressure treatment.BMC Pulm Med, 2012, 12:36. |
16. | Karamanll H, Öol D, Ugur KS, et al.Influence of CPAP treatment on airway and systemic inflammation in OSAS patients.Sleep Breath, 2014, 18:251-256. |
17. | Okur HK, Pelin Z, Yuksel M, et al.Lipid peroxidation and paraoxonase activity in nocturnal cyclic and sustained intermittent hypoxia.Sleep Breath, 2013, 17:365-371. |
18. | Papandreou C, Schiza SE, Tzatzarakis MN, et al.Effect of Mediterranean diet on lipid peroxidation marker TBARS in obese patients with OSAHS under CPAP treatment:a randomised trial.Sleep Breath, 2012, 16:873-879. |
19. | Lam JC, Tan KC, Lai AY, et al.Increased serum levels of advanced glycation end-products is associated with severity of sleep disordered breathing but not insulin sensitivity in non-diabetic men with obstructive sleep apnoea.Sleep Med, 2012, 13:15-20. |
20. | Kotani K, Kimura S, Komada I, et al.Continuous positive air pressure treatment reduces serum advanced glycation end products in patients with obstructive sleep apnoea syndrome:a pilot study.Prim Care Respir J, 2011, 20:336-337. |
21. | Guo Q, Wang Y, Li QY, et al.Levels of thioredoxin are related to the severity of obstructive sleep apnea:based on oxidative stress concept.Sleep Breath, 2013, 17:311-316. |
22. | Zhou W, Li S, Wan N, et al.Effects of various degrees of oxidative stress induced by intermittent hypoxia in rat myocardial tissues.Respirology, 2012, 17:821-829. |
23. | Ruiz GA, Sánchez AA, Luque CE.Blood uric acid levels in patients with sleep-disordered breathing.Arch Bronconeumol, 2006, 42:492-500. |
24. | Ryan S, McNicholas WT, Taylor CT.A critical role for p38 map kinase in NF-κB signaling during intermittent hypoxia/reoxygenation.Biochem Biophys Res Commun, 2007, 355:728-733. |
25. | Williams A, Scharf SM.Obstructive sleep anea, cardiovascular disease, and inflammation-is NF-κB the key? Sleep Breath, 2007, 11:69-76. |
26. | Yokoe T, Minoguchi K, Matsuo H, et al.Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure.Circulation, 2003, 107:1129-1134. |
27. | Can M, Açikgöz S, Mungan G, et al.Serum cardiovascular risk factors in obstructive sleep apnea.Chest, 2006, 129:233-237. |
28. | Punjabi NM, Beamer BA.C-reactive protein is associated with sleep disordered breathing independent of adiposity.Sleep, 2007, 30:29-34. |
29. | Lui MM, Lam JC, Mak HK, et al.C-reactive protein is associated with obstructive sleep apnea independent of visceral obesity.Chest, 2009, 135:950-956. |
30. | Steiropoulos P, Tsara V, Nena E, et al.Effect of continuous positive airway pressure treatment on serum cardiovascular risk factors in patients with obstructive sleep apnea-hypopnea syndrome.Chest, 2007, 132:843-851. |
31. | Burioka N, Miyata M, Fukuoka Y, et al.Day-night variations of serum interleukin-6 in patients with severe obstructive sleep apnea syndrome before and after continuous positive airway pressure (CPAP).Chronobiol Int, 2008, 25:827-834. |
32. | Sahlman J, Miettinen K, Peuhkurinen K, et al.The activation of the inflammatory cytokines in overweight patients with mild obstructive sleep apnoea.J Sleep Res, 2010, 19:341-348. |
33. | Barcelo A, Barbe F, Llompart E, et al.Effects of obesity on C-reactive protein level and metabolic disturbances in male patients with obstructive sleep apnea.Am J Med, 2004, 117:118-121. |
34. | Guilleminault C, Kirisoglu C, Ohayon MM.C-reactive protein and sleep-disordered breathing.Sleep, 2004, 27:1507-1511. |
35. | Taheri S, Austin D, Lin L, et al.Correlates of serum C-reactive protein (CRP)-no association with sleep duration or sleep disordered breathing.Sleep, 2007, 30:991-996. |
36. | Hotamisligil GS.Inflammatory pathways and insulin action.Int J Obes Relat Metab Disord, 2003, 27:53-55. |
37. | Maury E, Brichard SM.Adipokine dysregulation, adipose tissue in flammation and metabolic syndrome.Mol Cell Endocrinol, 2010, 314:1-16. |
38. | Arnardottir ES, Maislin G, Schwab RJ, et al.The interaction of obstructive sleep apnea and obesity on the inflammatory markers C-reactive protein and interleukin-6:The Icelandic Sleep Apnea Cohort.Sleep, 2012, 35:921-932. |
39. | Alberti A, Sarchielli P, Gallinella E, et al.Plasma cytokine levels in patients with obstructive sleep apnea syndrome:a preliminary study.J Sleep Res, 2003, 12:305-311. |
40. | Patel SR, Zhu X, Storfer-Isser A, et al.Sleep duration and biomarkers of inflammation.Sleep, 2009, 32:200. |
41. | Steiropoulos P, Kotsianidis I, Nena E, et al.Long-term effect of continuous positive airway pressure therapy on inflammation markers of patients with obstructive sleep apnea syndrome.Sleep, 2009, 32:537-543. |
42. | Ishida K, Kato M, Kato Y, et al.Appropriate use of nasal continuous positive airway pressure decreases elevated C-reactive protein in patients with obstructive sleep apnea.Chest, 2009;136:125-129. |
43. | Murase K, Mori K, Yoshimura C, et al.Association between plasma neutrophil gelatinase associated lipocalin level and obstructive sleep apnea or nocturnal intermittent hypoxia.PloS ONE, 2013, 8:e54184. |
44. | Cholidou KG, Kostakis ID, Manali ED, et al.Calprotectin:a protein related to cardiovascular risk in adult patients with obstructive sleep apnea.Cytokine, 2013, 61:917-923. |
45. | 何权瀛, 陈宝元, 张希龙.解读阻塞性睡眠呼吸暂停与糖尿病专家共识.中国实用内科学, 2010, 30:703-704. |
46. | Reichmuth KJ, Austin D, Skatrud JB, et al.Association of sleep apnea and typeⅡdiabetes:a population-based study.Am J Respir Crit Care Med, 2005, 172:1590-1595. |
47. | Foster GD, Sanders MH, Millman R, et al.Sleep AHEAD Research Group.Obstructive sleep apnea among obese patients with type 2 diabetes.Diabetes Care, 2009, 32:1017-1019. |
48. | 高莹慧, 何权瀛.睡眠呼吸暂停的诊治首次纳入美国临床内分泌医师学会糖尿病综合治疗方案指南.中华结核和呼吸杂志, 2011, 34:748. |
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54. | 臧淑妃, 潘志杰, 李成江.代谢综合征与阻塞性睡眠呼吸暂停低通气综合征独立相关.中华内分泌代谢杂志, 2008, 24:400-403. |
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56. | 叶亮, 李敏, 陈聆.阻塞性睡眠呼吸暂停低通气综合征患者血脂及血液流变学的变化.中华结核和呼吸杂志, 2009, 32:926-930. |
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63. | Al-Shaer MH, Shammas NW, Lemke JH, et al.CPAP does not reduce high-sensitivity C-reactive protein in patients with coronary artery disease and obstructive sleep apnea.Int J Angiol, 2005, 14:129-132. |
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- 1. Young T, Palm M, Dempsey J, et al.The occurrence of sleep-disordered breathing among middle-aged adults.N Engl J Med, 1993, 328:1230-1235.
- 2. 高维杰, 王彦, 孙玫, 等.持续气道正压通气治疗阻塞性睡眠呼吸暂停低通气综合征的依从性调查.中华结核和呼吸杂志, 2011, 34:68-69.
- 3. Krieger J.Long-term compliance with nasal continuous positive airway pressure (CPAP) in obstructive sleep apnea patients and nonapneic snorers.Sleep, 1992, 15(6 Suppl):S42-S46.
- 4. Sanders MH, Gruendl CA, Rogers RM.Patient compliance with nasal CPAP therapy for sleep apnea.Chest, 1986, 90:330-333.
- 5. Weaver TE, Kribbs NB, Pack AI, et al.Night-to-night variability in CPAP use over first three months of treatment.Sleep, 1997, 20:278-283.
- 6. 孙士波, 郝青林, 徐鸥, 等.长期自动调节压力持续正压通气治疗阻塞性睡眠呼吸暂停低通气综合征的临床观察.国际呼吸杂志, 2012, 32:201-203.
- 7. 李庆云.慢性间歇低氧与氧化应激.中华结核和呼吸杂志, 2009, 32:646-647.
- 8. 郭雪玲, 刘辉国.慢性间歇低氧血管内皮功能障碍与氧化应激的关系研究进展.中华结核和呼吸杂志, 2012, 35:203-206.
- 9. Simiakakis M, Kapsimalis F, Chaligiannis E, et al.Lack of effect of sleep apnea on oxidative stress in obstructive sleep apnea syndrome (OSAHS) patients.PLoS ONE, 2012, 7:e39172.
- 10. Carpagnano GE, Kharitonov SA, Resta O, et al.Increased 8-isoprostane and interleukin-6 in breath condensate of obstructive sleep apnea patients.Chest, 2002, 122:1162-1167.
- 11. Carpagnano GE, Kharitonov SA, Resta O, et al.8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy.Chest, 2003, 124:1386-1392.
- 12. Weiss JW, Liu Y, Li X, et al.Nitric oxide and obstructive sleep apnea. Respir Physiol Neurobiol, 2012, 184:192-196.
- 13. Ip MS, Lam B, Chan LY, et al.Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure.Am J Respir Crit Care Med, 2000, 162:2166-2171.
- 14. Alonso-Fernández A, García-Río F, Arias MA, et al.Effects of CPAP on oxidative stress and nitrate efficiency in sleep apnoea:a randomized trial.Thorax, 2009, 64:581-586.
- 15. Del Ben M, Fabiani M, Loffredo L, et al.Oxidative stress mediated arterial dysfunction in patients with obstructive sleep apnoea and the effect of continuous positive airway pressure treatment.BMC Pulm Med, 2012, 12:36.
- 16. Karamanll H, Öol D, Ugur KS, et al.Influence of CPAP treatment on airway and systemic inflammation in OSAS patients.Sleep Breath, 2014, 18:251-256.
- 17. Okur HK, Pelin Z, Yuksel M, et al.Lipid peroxidation and paraoxonase activity in nocturnal cyclic and sustained intermittent hypoxia.Sleep Breath, 2013, 17:365-371.
- 18. Papandreou C, Schiza SE, Tzatzarakis MN, et al.Effect of Mediterranean diet on lipid peroxidation marker TBARS in obese patients with OSAHS under CPAP treatment:a randomised trial.Sleep Breath, 2012, 16:873-879.
- 19. Lam JC, Tan KC, Lai AY, et al.Increased serum levels of advanced glycation end-products is associated with severity of sleep disordered breathing but not insulin sensitivity in non-diabetic men with obstructive sleep apnoea.Sleep Med, 2012, 13:15-20.
- 20. Kotani K, Kimura S, Komada I, et al.Continuous positive air pressure treatment reduces serum advanced glycation end products in patients with obstructive sleep apnoea syndrome:a pilot study.Prim Care Respir J, 2011, 20:336-337.
- 21. Guo Q, Wang Y, Li QY, et al.Levels of thioredoxin are related to the severity of obstructive sleep apnea:based on oxidative stress concept.Sleep Breath, 2013, 17:311-316.
- 22. Zhou W, Li S, Wan N, et al.Effects of various degrees of oxidative stress induced by intermittent hypoxia in rat myocardial tissues.Respirology, 2012, 17:821-829.
- 23. Ruiz GA, Sánchez AA, Luque CE.Blood uric acid levels in patients with sleep-disordered breathing.Arch Bronconeumol, 2006, 42:492-500.
- 24. Ryan S, McNicholas WT, Taylor CT.A critical role for p38 map kinase in NF-κB signaling during intermittent hypoxia/reoxygenation.Biochem Biophys Res Commun, 2007, 355:728-733.
- 25. Williams A, Scharf SM.Obstructive sleep anea, cardiovascular disease, and inflammation-is NF-κB the key? Sleep Breath, 2007, 11:69-76.
- 26. Yokoe T, Minoguchi K, Matsuo H, et al.Elevated levels of C-reactive protein and interleukin-6 in patients with obstructive sleep apnea syndrome are decreased by nasal continuous positive airway pressure.Circulation, 2003, 107:1129-1134.
- 27. Can M, Açikgöz S, Mungan G, et al.Serum cardiovascular risk factors in obstructive sleep apnea.Chest, 2006, 129:233-237.
- 28. Punjabi NM, Beamer BA.C-reactive protein is associated with sleep disordered breathing independent of adiposity.Sleep, 2007, 30:29-34.
- 29. Lui MM, Lam JC, Mak HK, et al.C-reactive protein is associated with obstructive sleep apnea independent of visceral obesity.Chest, 2009, 135:950-956.
- 30. Steiropoulos P, Tsara V, Nena E, et al.Effect of continuous positive airway pressure treatment on serum cardiovascular risk factors in patients with obstructive sleep apnea-hypopnea syndrome.Chest, 2007, 132:843-851.
- 31. Burioka N, Miyata M, Fukuoka Y, et al.Day-night variations of serum interleukin-6 in patients with severe obstructive sleep apnea syndrome before and after continuous positive airway pressure (CPAP).Chronobiol Int, 2008, 25:827-834.
- 32. Sahlman J, Miettinen K, Peuhkurinen K, et al.The activation of the inflammatory cytokines in overweight patients with mild obstructive sleep apnoea.J Sleep Res, 2010, 19:341-348.
- 33. Barcelo A, Barbe F, Llompart E, et al.Effects of obesity on C-reactive protein level and metabolic disturbances in male patients with obstructive sleep apnea.Am J Med, 2004, 117:118-121.
- 34. Guilleminault C, Kirisoglu C, Ohayon MM.C-reactive protein and sleep-disordered breathing.Sleep, 2004, 27:1507-1511.
- 35. Taheri S, Austin D, Lin L, et al.Correlates of serum C-reactive protein (CRP)-no association with sleep duration or sleep disordered breathing.Sleep, 2007, 30:991-996.
- 36. Hotamisligil GS.Inflammatory pathways and insulin action.Int J Obes Relat Metab Disord, 2003, 27:53-55.
- 37. Maury E, Brichard SM.Adipokine dysregulation, adipose tissue in flammation and metabolic syndrome.Mol Cell Endocrinol, 2010, 314:1-16.
- 38. Arnardottir ES, Maislin G, Schwab RJ, et al.The interaction of obstructive sleep apnea and obesity on the inflammatory markers C-reactive protein and interleukin-6:The Icelandic Sleep Apnea Cohort.Sleep, 2012, 35:921-932.
- 39. Alberti A, Sarchielli P, Gallinella E, et al.Plasma cytokine levels in patients with obstructive sleep apnea syndrome:a preliminary study.J Sleep Res, 2003, 12:305-311.
- 40. Patel SR, Zhu X, Storfer-Isser A, et al.Sleep duration and biomarkers of inflammation.Sleep, 2009, 32:200.
- 41. Steiropoulos P, Kotsianidis I, Nena E, et al.Long-term effect of continuous positive airway pressure therapy on inflammation markers of patients with obstructive sleep apnea syndrome.Sleep, 2009, 32:537-543.
- 42. Ishida K, Kato M, Kato Y, et al.Appropriate use of nasal continuous positive airway pressure decreases elevated C-reactive protein in patients with obstructive sleep apnea.Chest, 2009;136:125-129.
- 43. Murase K, Mori K, Yoshimura C, et al.Association between plasma neutrophil gelatinase associated lipocalin level and obstructive sleep apnea or nocturnal intermittent hypoxia.PloS ONE, 2013, 8:e54184.
- 44. Cholidou KG, Kostakis ID, Manali ED, et al.Calprotectin:a protein related to cardiovascular risk in adult patients with obstructive sleep apnea.Cytokine, 2013, 61:917-923.
- 45. 何权瀛, 陈宝元, 张希龙.解读阻塞性睡眠呼吸暂停与糖尿病专家共识.中国实用内科学, 2010, 30:703-704.
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