嗅神经母细胞瘤源性气管支气管转移瘤一例报告并文献复习_Chinese Journal of Respiratory and Critical Care Medicine

Authors：

张伟 , 杨梦 ,  李强

上海长海医院呼吸与危重症医学科（上海 200433）;

Corresponding author：

李强, Email: liqressh@hotmail.com

Keywords：

嗅神经母细胞瘤; 气管支气管转移瘤; 支气管介入治疗

DOI：

10.7507/1671-6205.2016018

Video：

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目的总结嗅神经母细胞瘤源性气管支气管转移瘤的诊断及治疗现状。方法报道我院收治的1例嗅神经母细胞瘤源性气管支气管转移瘤患者, 并查阅相关报道资料进行文献复习与总结。结果患者男性, 55岁, 因"咳嗽2个月, 伴气促、声音嘶哑半个月"收治入院。外院颈部及胸部CT示气管上段新生物(2个), 气管重度阻塞。入院后行电子支气管镜示气管内新生物, 气管重度狭窄。行镜下病理活检, 新生物行圈套、基底部高频电凝及氩离子束凝固术。患者经支气管镜治疗后, 咳嗽、气促症状缓解, 病情稳定。3个月后出现右中肺、左肺、纵隔淋巴结及左侧胸膜多发转移瘤。患者拒绝进一步治疗, 自动出院。结论对于既往有肺外恶性肿瘤史的患者, 当其出现咳嗽、咯血、呼吸困难等呼吸道相关症状时, 除考虑肺部转移外, 也应考虑气管支气管转移, 尽快予以影像学检查、支气管镜检, 甚至病理及免疫组化活检等明确诊断。及早积极治疗有助于改善气管支气管转移瘤患者生存质量甚至预后。

Citation： 张伟, 杨梦, 李强. 嗅神经母细胞瘤源性气管支气管转移瘤一例报告并文献复习. Chinese Journal of Respiratory and Critical Care Medicine, 2016, 15(1): 75-77. doi: 10.7507/1671-6205.2016018 Copy

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10.	王西华, 李萍, 李名娣, 等.支气管转移癌的内镜下表现和病理诊断.中国内镜杂志, 2014, 20:381-384.
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13.	王莉.气管支气管转移癌78例临床分析.临床医学, 2014, 34:42-43.
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15.	刘晓琴, 王琪, 房居高.嗅神经母细胞瘤的诊治进展, 2013, 37:122-124.
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1. Kiryu T, Hoshi H, Matsui E, et al.Endotracheal/endobronchial metastases:clinicopathologic study with special reference to developmental modes.Chest, 2001, 119:768-775.
2. Marchioni A, Lasagni A, Busca A, et al.Endobronchial metastasis:An epidemiologic and clinicopathologic study of 174 consecutive cases.Lung Cancer, 2014, 84:222-228.
3. Klas JV, Rothenberger DA, Wond WD, et al. Malignant tumors of the anal canal:the spectrum of disease, treatment and outcomes.Cancer, 1999, 85:1686-1693.
4. Kreisman H, Wolkove N, Finkelstein HS, et al.Breast cancer and thoracic metastases:review of 119 patients.Thorax, 1983, 38:175-179.
5. Willis RA.The spread of tumors in the human body.Lancet, 1973, 1(8482):683-684.
6. Braman SS, Whitcomb ME.Endobronchial metastasis.Arch Intern Med, 1975, 135:543-547.
7. Sorensen JB.Endobronchial metastases from extrapulmonary solid tumors.Acta Oncologica, 2003, 43:73-79.
8. Salud A, Porcel JM, Rovirosa A, et al.Endobronchial metastatic disease.Analysis of 32 cases.J Surg Oncol, 1996, 62:249-252.
9. Lee SH, Jung JY, Kim DH, et al.Endobronchial metastases from extrathoracic malignancy.Yonsei Med J, 2013, 54:403-409.
10. 王西华, 李萍, 李名娣, 等.支气管转移癌的内镜下表现和病理诊断.中国内镜杂志, 2014, 20:381-384.
11. 项瑞芬.气管支气管转移癌临床分析.中国现代药物应用, 2013, 7:74-75.
12. 白冲, 黄怡, 李强, 等.气管支气管转移癌62例临床分析.中华内科杂志, 2007, 46:806-809.
13. 王莉.气管支气管转移癌78例临床分析.临床医学, 2014, 34:42-43.
14. Dong A, Zhao T, Wang Y, et al.FDG PET/CT in endobronchial metastases fromextrathoracic malignancies.Clin Nucl Med, 2014, 39:446-449.
15. 刘晓琴, 王琪, 房居高.嗅神经母细胞瘤的诊治进展, 2013, 37:122-124.
16. Carlin BW, Harrell JH 2nd, Olson LK, et al.Endobronchial metastases due to colorectal carcinoma.Chest, 1989, 96:1110-1114.
17. Quantrill SJ, Burt PA, Barber PV, et al.Treatment of endobronchial metastases with intraluminal radiotherapy.Respir Med, 2000, 94:369-372.

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嗅神经母细胞瘤源性气管支气管转移瘤一例报告并文献复习

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