Weifuchun for Chronic Atrophic Gastritis: A Systematic Review_Chinese Journal of Evidence-Based Medicine

Authors：

ZHU Liangliang ¹² , TIAN Jinhui ²³ , BAI Zhenggang ²³ , YANG Kehu ²³ , WU Jing ²⁴ , ZHAO Fenghui ¹² ,  MA Bin ²³

1. School of Public Health, Lanzhou University, Lanzhou 730000, China;2. Evidence-Based Medicine Center of Lanzhou University, Lanzhou 730000, China;3. School of Basic Medicine, Lanzhou University, Lanzhou 730000, China;4. School of Clinical Medicine, Lanzhou University, Lanzhou 730000, China;

Corresponding author：

MA Bin, Email: kitty_mab@163.com

Keywords：

Weifuchun; Chronic atrophic gastritis; Systematic review

DOI：

10.7507/1672-2531.20090017

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Objective 　To assess the effectiveness and safety of Weifuchun for chronic atrophic gastritis.
Methods 　Trials were located through electronic searches of The Cochrane Library (Issue 3, 2007), EMbase (1974 to June 2007), PubMed (1966 to June 2007), CBM (1978 to June 2007), CNKI (1994 to June 2007) and VIP (1989 to June 2007). Randomized controlled trials (RCTs) and quasi-RCTs of Weifuchun for chronic atrophic gastritis were included. A critical quality assessment and Meta-analysis were performed for the included studies. RevMan 4.2.2 was used for statistical analysis.
Results 　A total of 8 trials involving 816 patients were included. Meta-analysis showed that compared with the control group, Weifuchun for the CAG treatment group had superiority in many aspects such as effective rate according to Gastroscopy (RR 1.54 and 95%CI 1.31 to 1.81), effective rate according to Patho-check (RR 1.99 and 95%CI 1.54 to 2.58), adverse events, remission rate based on clinical symptoms (RR 1.47 and 95%CI 1.30 to 156), remission rate based on a single symptom, curative effect with IM/ATP, HP darkening rate (RR 1.26 and 95%CI 1.02 to 1.56), situation of hemoglobin change and so on. No RCTs were found to describe the safety of Weifuchun for CAG.
Conclusion 　 Because of low quality and small samples, there is no enough evidence on Weifuchun for chronic atrophic gastritis. More largescale multi-center randomized trials are needed to investigate the role of Weifuchun for chronic atrophic gastritis.

Citation： ZHU Liangliang,TIAN Jinhui,BAI Zhenggang,YANG Kehu,WU Jing,ZHAO Fenghui,MA Bin. Weifuchun for Chronic Atrophic Gastritis: A Systematic Review. Chinese Journal of Evidence-Based Medicine, 2009, 09(1): 81-87. doi: 10.7507/1672-2531.20090017 Copy

1.	秦晓波. 幽门螺杆菌联合胃复春对萎缩性胃炎的疗效. 中国医药导报, 2007, 4(6): 54-62.
2.	王敏. 慢性萎缩性胃炎的治疗概况与前景. 2006年消化系统疾病学术年会暨胰腺疾病专题讲座论文汇编.
3.	姒健敏. 慢性萎缩性胃炎的诊断、癌变监测和干预治疗. 2005年浙江省消化系疾病学术会议论文汇编. 19-22.
4.	徐维维, 王闽全. 胃复春片治疗慢性萎缩性胃炎疗效观察. 浙江中西医结合杂志, 2003, 13(8): 505-506.
5.	历兰娜, 赵树珍. 胃复春片对慢性萎缩性胃炎血浆环磷酸腺苷 (CAMP)的影响. 中国实用中西医结合杂志, 1993, (7): 6.
6.	李艳萍. 维酶素的研究进展. 西北药学杂志, 2002, 17(3): 140-141.
7.	赵红, 周学锋. 胃复春治疗慢性萎缩性胃炎癌前病变144例. 中国药业, 2004, 8(13): 70.
8.	厉兰娜, 赵树珍, 江汉才, 等. 胃复春治疗胃癌前期病变41例临床观察. 中国中医药科技, 1996, 6(3): 38-39.
9.	马贵同, 姚洁明, 张达荣. 胃复春片治疗慢性萎缩性胃炎的临床观察. 上海中医药杂志, 1995, 10: 28-29.
10.	张运贵, 孙兆田, 姚桂芹, 等. 胃复春治疗胃粘膜异型增生临床观察及对P21ras和P53表达的调节作用. 中国中西医结合消化杂志, 2004, 2(12): 95-97.
11.	邬虹敏. 胃复春片治疗慢性萎缩性胃炎临床观察. 中国厂矿医学, 2000, 3(13): 215-216.
12.	陈之光, 张梅芬. 中西医结合治疗慢性萎缩性胃炎68例疗效观察. 浙江中医学院学报, 2000, 4(24): 28.
13.	王卫和. 复春片治疗慢性萎缩性胃炎的对比观察. 北京医学, 2000, 1(22): 19.
14.	赵俊英. 胃复春片治疗慢性萎缩性胃炎58 例疗效观察. 山东医药, 2003, 32(43): 15.
15.	彭罗瑞, 李新华. 自拟理气活血益胃汤治疗慢性萎缩性胃炎60例分析. 甘肃中医, 2006, 4(19): 19-21.

1. 秦晓波. 幽门螺杆菌联合胃复春对萎缩性胃炎的疗效. 中国医药导报, 2007, 4(6): 54-62.
2. 王敏. 慢性萎缩性胃炎的治疗概况与前景. 2006年消化系统疾病学术年会暨胰腺疾病专题讲座论文汇编.
3. 姒健敏. 慢性萎缩性胃炎的诊断、癌变监测和干预治疗. 2005年浙江省消化系疾病学术会议论文汇编. 19-22.
4. 徐维维, 王闽全. 胃复春片治疗慢性萎缩性胃炎疗效观察. 浙江中西医结合杂志, 2003, 13(8): 505-506.
5. 历兰娜, 赵树珍. 胃复春片对慢性萎缩性胃炎血浆环磷酸腺苷 (CAMP)的影响. 中国实用中西医结合杂志, 1993, (7): 6.
6. 李艳萍. 维酶素的研究进展. 西北药学杂志, 2002, 17(3): 140-141.
7. 赵红, 周学锋. 胃复春治疗慢性萎缩性胃炎癌前病变144例. 中国药业, 2004, 8(13): 70.
8. 厉兰娜, 赵树珍, 江汉才, 等. 胃复春治疗胃癌前期病变41例临床观察. 中国中医药科技, 1996, 6(3): 38-39.
9. 马贵同, 姚洁明, 张达荣. 胃复春片治疗慢性萎缩性胃炎的临床观察. 上海中医药杂志, 1995, 10: 28-29.
10. 张运贵, 孙兆田, 姚桂芹, 等. 胃复春治疗胃粘膜异型增生临床观察及对P21ras和P53表达的调节作用. 中国中西医结合消化杂志, 2004, 2(12): 95-97.
11. 邬虹敏. 胃复春片治疗慢性萎缩性胃炎临床观察. 中国厂矿医学, 2000, 3(13): 215-216.
12. 陈之光, 张梅芬. 中西医结合治疗慢性萎缩性胃炎68例疗效观察. 浙江中医学院学报, 2000, 4(24): 28.
13. 王卫和. 复春片治疗慢性萎缩性胃炎的对比观察. 北京医学, 2000, 1(22): 19.
14. 赵俊英. 胃复春片治疗慢性萎缩性胃炎58 例疗效观察. 山东医药, 2003, 32(43): 15.
15. 彭罗瑞, 李新华. 自拟理气活血益胃汤治疗慢性萎缩性胃炎60例分析. 甘肃中医, 2006, 4(19): 19-21.

Previous Article
卡泊芬净治疗IgA肾病并发肺孢子菌肺炎一例
Next Article
胸腺瘤术后发生弥漫性泛细支气管炎一例

Chinese Journal of Evidence-Based Medicine

Weifuchun for Chronic Atrophic Gastritis: A Systematic Review

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content