Objective To evaluate the clinical value of cardiac MRI for the diagnosis of viral myocarditis (VMC).
Methods Such databases as PubMed (1950 to 2009), EMbase (1974 to 2009), and The Cochrane Library (December 2009) were searched to include clinical research reports of diagnosing viral myocarditis with MRI. QUADAS items were used to evaluate the quality of the included studies. The Meta-disc software was used to conduct merger analyses on sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio. The Heterogeneity test was performed and summary receiver operating characteristic curve (SROC) was completed.
Results Five trials were included. The value of merger sensitivity, specificity, and diagnostic odds ratio (DOR) were 0.94, 0.69, 2.76, and 28.11, respectively. The area under of SROC curve (AUC) was 0.871 9.
Conclusion The current evidence shows that cardiac MRI has high sensitivity (94%) and moderate specificity (69%) in the diagnosis of viral myocarditis. The positive rate in the viral myocarditis group is 28.11 times as high as that in the non-viral myocarditis group, so Cardiac MRI has good diagnostic values for viral myocarditis.
Citation: DING Binbin,ZHANG Junping. Diagnostic Value of Cardiac MRI for Viral Myocarditis: A Systematic Review. Chinese Journal of Evidence-Based Medicine, 2011, 11(3): 273-277. doi: 10.7507/1672-2531.20110046 Copy