Sternocleidomastoid Muscle Flap in Preventing Gustatory Sweating Syndrome Following Parotidectomy: A Meta-Analysis_Chinese Journal of Evidence-Based Medicine

Authors：

LIU Ping ¹ , JIA Yurong ² ,  ZHANG Shuxiang ¹

1. Department of Otorhinolaryngology, The Affiliated Hospital of Logistics College of Chinese People’s Armed Police Force, Tianjin 300162, China;2. Department of Radiology, The Affiliated Hospital of Logistics College of Chinese People’s Armed Police Force, Tianjin 300162, China;

Corresponding author：

ZHANG Shuxiang, Email: sxfxajy@163.com

Keywords：

Sternocleidomastoid muscle flap; Gustatory sweating syndrome (Frey syndrome); Parotidectomy; Meta-analysis; GRADE

DOI：

10.7507/1672-2531.20120216

Video：

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Abstract Full text Figures/Tables Video References Cited by

Objective 　To assess the effectiveness of sternocleidomastoid muscle (SCM) flap in preventing gustatory sweating syndrome following parotidectomy.
Methods 　Databases including The Cochrane Library, MEDLINE, EMbase, CBM, CNKI, VIP and WanFang Data were searched from inception to March 2012 to retrieve randomized controlled trials (RCTs) about SCM flap in preventing gustatory sweating syndrome following parotidectomy. The data of studies meeting the inclusion criteria were extracted by two reviewers independently, the methodological quality was assessed and cross-checked, and meta-analysis was performed using the RevMan 5.1 software.
Results 　A total of 10 RCTs involving 825 patients were included. The results of meta-analyses showed that compared with the blank control group, SCM flap could obviously decrease the subjective incidence of gustatory sweating syndrome by 78% (OR=0.22, 95%CI 0.08 to 0.59, P=0.003) and the objective incidence by 83% (OR=0.17, 95%CI 0.05 to 0.60, P=0.006). The sensitivity analysis indicated the above results were robust. The evidence based on GRADE system was of “low quality”. There was no obvious publication bias according to the tunnel chart.
Conclusions 　Current evidence shows that SCM flap can obviously decrease both subjective and objective incidence of gustatory sweating syndrome following parotidectomy. Considering the limitation of the included studies, this conclusion still needs to be tested by more large-scale and high-quality RCTs taking SCM function as one of the outcome.

Citation： LIU Ping,JIA Yurong,ZHANG Shuxiang. Sternocleidomastoid Muscle Flap in Preventing Gustatory Sweating Syndrome Following Parotidectomy: A Meta-Analysis. Chinese Journal of Evidence-Based Medicine, 2012, 12(11): 1385-1390. doi: 10.7507/1672-2531.20120216 Copy

1.	de Bree R, van der Waal I, Leemans CR. Management of Frey syndrome. Head Neck, 2007, 29(8): 773-778.
2.	Emeryk-Szajewska B. Lucja Frey-Gottesman - discoverer of Frey’s syndrome and her tragic fate. Neurol Neurochir Pol, 2011, 45(4): 407-412.
3.	Rustemeyer J, Eufinger H, Bremerich A. The incidence of Frey’s syndrome. J Craniomaxillofac Surg, 2008, 36(1): 34-37.
4.	Hartl DM, Julieron M, LeRidant AM, et al. Botulinum toxin A for quality of life improvement in post-parotidectomy gustatory sweating (Frey’s syndrome). J Laryngol Otol, 2008, 122(10): 1100-1104.
5.	Guntinas-Lichius O, Gabriel B, Klussmann JP. Risk of facial palsy and severe Frey’s syndrome after conservative parotidectomy for benign disease: analysis of 610 operations. Acta Otolaryngol, 2006, 126(10): 1104-1109.
6.	Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from: http://www.cochrane-handbook.org.
7.	Kerawala CJ, McAloney N, Stassen LF. Prospective randomised trial of the benefits of a sternocleidomastoid flap after superficial parotidectomy. Br J Oral Maxillofac Surg, 2002, 40(6): 468-472.
8.	陈睿, 杨凯. 胸锁乳突肌瓣对腮腺术后缺损的修复及对Frey综合征预防的疗效观察. 2004, 33(1): 94-95.
9.	Asal K, Köybaşioğlu A, Inal E, et al. Sternocleidomastoid muscle flap reconstruction during parotidectomy to prevent Frey’s syndrome and facial contour deformity. Ear Nose Throat J, 2005, 84(3): 173-176.
10.	Zhao HW, Li LJ, Han B, et al. A retrospective study on the complications after modified parotidectomy in benign tumors of parotid gland. Hua Xi Kou Qiang Yi Xue Za Zhi, 2005, 23(1): 53-56.
11.	郅克谦, 温玉明, 李龙江. 腮腺良性肿瘤切除后并发症的防治. 西安交通大学学报(医学版), 2007, 28(1): 116-117.
12.	丁月峰, 周培刚, 顾永春, 等. 胸锁乳突肌瓣在腮腺良性肿瘤切除术中的应用. 广东牙病防治, 2010, 18(2): 88-90.
13.	廖圣恺, 李建成, 张凯, 等. 胸锁乳突肌肌瓣修复腮腺肿瘤术后缺损48例效果观察. 2010, 3(2): 106-107.
14.	邓永强, 郑苍尚, 朱耀旻. 胸锁乳突肌瓣和腮腺筋膜瓣联合应用对腮腺良性肿瘤术后并发症的预防作用. 口腔医学研究, 2011, 27(10): 893-895.
15.	彭云烽, 陈云东. 腮腺肿瘤45例的临床分析. 中外健康文摘, 2011, 8(45): 241.
16.	赵健, 余洪强, 刘阿贵. 异种脱细胞真皮基质与重建腮腺嚼肌筋膜预防腮腺切除术后味觉出汗综合征的比较研究. 口腔医学, 2011, 31(6): 356-359.
17.	曾宪涛, 冷卫东, 李胜, 等. 如何正确理解及使用GRADE系统. 中国循证医学杂志, 2011, 11(9): 985-990.
18.	曾宪涛, 田国祥, 牛玉明, 等. GRADEprofiler软件的使用简介. 中国循证心血管医学杂志, 2011, 3(5): 390-392.
19.	曾宪涛, 郭毅, 夏凌云, 等. 脱细胞真皮基质预防Frey综合征的系统评价. 中国循证医学杂志, 2011, 11(1): 76-83.
20.	Sanabria A, Kowalski LP, Bradley PJ, et al. Sternocleidomastoid muscle flap in preventing Frey’s syndrome after parotidectomy: a systematic review. Head Neck, 2012, 34(4): 589-598.
21.	Curry JM, King N, Reiter D, et al. Meta-analysis of surgical techniques for preventing parotidectomy sequelae. Arch Facial Plast Surg, 2009, 11(5): 327-331.

1. de Bree R, van der Waal I, Leemans CR. Management of Frey syndrome. Head Neck, 2007, 29(8): 773-778.
2. Emeryk-Szajewska B. Lucja Frey-Gottesman - discoverer of Frey’s syndrome and her tragic fate. Neurol Neurochir Pol, 2011, 45(4): 407-412.
3. Rustemeyer J, Eufinger H, Bremerich A. The incidence of Frey’s syndrome. J Craniomaxillofac Surg, 2008, 36(1): 34-37.
4. Hartl DM, Julieron M, LeRidant AM, et al. Botulinum toxin A for quality of life improvement in post-parotidectomy gustatory sweating (Frey’s syndrome). J Laryngol Otol, 2008, 122(10): 1100-1104.
5. Guntinas-Lichius O, Gabriel B, Klussmann JP. Risk of facial palsy and severe Frey’s syndrome after conservative parotidectomy for benign disease: analysis of 610 operations. Acta Otolaryngol, 2006, 126(10): 1104-1109.
6. Higgins JPT, Green S (editors). Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from: http://www.cochrane-handbook.org.
7. Kerawala CJ, McAloney N, Stassen LF. Prospective randomised trial of the benefits of a sternocleidomastoid flap after superficial parotidectomy. Br J Oral Maxillofac Surg, 2002, 40(6): 468-472.
8. 陈睿, 杨凯. 胸锁乳突肌瓣对腮腺术后缺损的修复及对Frey综合征预防的疗效观察. 2004, 33(1): 94-95.
9. Asal K, Köybaşioğlu A, Inal E, et al. Sternocleidomastoid muscle flap reconstruction during parotidectomy to prevent Frey’s syndrome and facial contour deformity. Ear Nose Throat J, 2005, 84(3): 173-176.
10. Zhao HW, Li LJ, Han B, et al. A retrospective study on the complications after modified parotidectomy in benign tumors of parotid gland. Hua Xi Kou Qiang Yi Xue Za Zhi, 2005, 23(1): 53-56.
11. 郅克谦, 温玉明, 李龙江. 腮腺良性肿瘤切除后并发症的防治. 西安交通大学学报(医学版), 2007, 28(1): 116-117.
12. 丁月峰, 周培刚, 顾永春, 等. 胸锁乳突肌瓣在腮腺良性肿瘤切除术中的应用. 广东牙病防治, 2010, 18(2): 88-90.
13. 廖圣恺, 李建成, 张凯, 等. 胸锁乳突肌肌瓣修复腮腺肿瘤术后缺损48例效果观察. 2010, 3(2): 106-107.
14. 邓永强, 郑苍尚, 朱耀旻. 胸锁乳突肌瓣和腮腺筋膜瓣联合应用对腮腺良性肿瘤术后并发症的预防作用. 口腔医学研究, 2011, 27(10): 893-895.
15. 彭云烽, 陈云东. 腮腺肿瘤45例的临床分析. 中外健康文摘, 2011, 8(45): 241.
16. 赵健, 余洪强, 刘阿贵. 异种脱细胞真皮基质与重建腮腺嚼肌筋膜预防腮腺切除术后味觉出汗综合征的比较研究. 口腔医学, 2011, 31(6): 356-359.
17. 曾宪涛, 冷卫东, 李胜, 等. 如何正确理解及使用GRADE系统. 中国循证医学杂志, 2011, 11(9): 985-990.
18. 曾宪涛, 田国祥, 牛玉明, 等. GRADEprofiler软件的使用简介. 中国循证心血管医学杂志, 2011, 3(5): 390-392.
19. 曾宪涛, 郭毅, 夏凌云, 等. 脱细胞真皮基质预防Frey综合征的系统评价. 中国循证医学杂志, 2011, 11(1): 76-83.
20. Sanabria A, Kowalski LP, Bradley PJ, et al. Sternocleidomastoid muscle flap in preventing Frey’s syndrome after parotidectomy: a systematic review. Head Neck, 2012, 34(4): 589-598.
21. Curry JM, King N, Reiter D, et al. Meta-analysis of surgical techniques for preventing parotidectomy sequelae. Arch Facial Plast Surg, 2009, 11(5): 327-331.

Chinese Journal of Evidence-Based Medicine

Sternocleidomastoid Muscle Flap in Preventing Gustatory Sweating Syndrome Following Parotidectomy: A Meta-Analysis

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