Two-in-One for Evaluation of Traditional Chinese Medicine as Adjuvant Therapy of Cancer: An New Method_Chinese Journal of Evidence-Based Medicine

Authors：

ZHAI Jingbo , REN Ming , CAO Hongbo , WANG Hui , LIU Chunxiang , LIU Zhi ,  SHANG Hongcai

Traditional Chinese Medicine of Tianjin University, Tianjin 300193, China;

Corresponding author：

SHANG Hongcai, Email: shanghongcai@foxmail.com

Keywords：

Dynamic individual information; Combined value; Adjuvant therapy of cancer; Evaluation method; Two-in-One

DOI：

10.7507/1672-2531.20130219

Video：

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Traditional Chinese medicine (TCM) has some unique advantages in the prevention and treatment of cancer. Due to different ideas and mechanism of between TCM and biomedicine in the prevention and treatment of cancer, the clinial effect evaluation approches of biomedicine could not be used as a beneficial method to scientifically evaluate the effects of TCM. From three angles, this article analyzes the key issues regardsing the evaluation methods of TCM as an adjuvant therapy of cancer. It draws lessons from the idea of quality-adjusted survival (QAS), proposes Two-in-One (TIO) method to evaluate the effects of TCM as adjuvant therapy of cancer, which reflects the combined value of the individual patient dynamic information and provides methodological support for the effect evaluation of TCM.

Citation： ZHAI Jingbo,REN Ming,CAO Hongbo,WANG Hui,LIU Chunxiang,LIU Zhi,SHANG Hongcai. Two-in-One for Evaluation of Traditional Chinese Medicine as Adjuvant Therapy of Cancer: An New Method. Chinese Journal of Evidence-Based Medicine, 2013, 13(11): 1280-1282. doi: 10.7507/1672-2531.20130219 Copy

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1. 赫捷, 赵平, 陈万青. 2012中国肿瘤登记年报. 军事医学科学出版社, 北京, 2012.
2. 郑文科. 中医药在防治肿瘤中的特色和优势. 天津中医药大学学报, 2010, 29(3): 166-168.
3. 鲁恒心, 方肇勤. 从现代医学治疗肿瘤的缺陷谈中医药的优势. 辽宁中医杂志, 2011, 28(7): 394-395.
4. 苏婉, 徐振晔. 肿瘤靶向治疗与中药多靶点效应的研究进展. 上海中医药杂志, 2007, 41(9): 87-88.
5. Cole BF, Glantz MJ, Jaeckle KA, et al. Quality-of-Life-Adjusted Survival Comparison of Sustained-Release Cytosine Arabinoside Versus Intrathecal Methotrexate for Treatment of Solid Tumor Neoplastic Meningitis. Cancer, 2003, 97(12): 3053-3060.
6. 王家良. 循证医学. 北京: 人民卫生出版社, 2006.
7. Sherrill B, Amonkar MM, Stein S, et al. Q-TWiST analysis of lapatinib combined with capecitabine for the treatment of metastatic breast cancer. Br J Cancer, 2008, 99(5): 711-715.
8. 赫元涛, 方积乾. 生存质量研究资料的统计分析. 中国肿瘤, 2001, 10(2): 72-75.
9. Weinstein MC, Torrance G, McGuire A. QALYs: the basics. Value Health, 2010, 13(8): 1065.
10. Bernhard J, Zahrieh D, Coates AS, et al. Quantifying trade-offs: quality of life and quality-adjusted survival in a randomised trial of chemotherapy in postmenopausal patients with lymph node-negative breast cancer. Br J Cancer, 2004, 91(11): 1893-1901.
11. 胡国清, 黄琼峰, 黄镇南, 等. 临床研究中最小临床意义变化值确定方法. 中南大学学报, 2009, 34(11): 1058-1062.
12. Adamchic I, Tass PA, Langguth B, et al. Linking the Tinnitus Questionnaire and the subjective Clinical Global Impression: Which differences are clinically important? Health Qual Life Outcomes, 2012, 10: 79.
13. Oliver A. Putting the quality into quality-adjusted life years. J Public Health Med, 2003, 25(1): 8-12.

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Two-in-One for Evaluation of Traditional Chinese Medicine as Adjuvant Therapy of Cancer: An New Method

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