• 1. Department of Clinical Pharmacy, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China;
  • 2. Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
  • 3. Evidence-based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
  • 4. Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China;
ZHANGJun, Email: sy-nawy@sina.com
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Objective To systematically assess the quality of evidence-based clinical guidelines and to compare the differences and similarities between recommendations, so as to provide references for clinical application. Methods Databases such as the TRIP, PubMed, CNKI, VIP, WanFang Data, CBM, National Guideline Clearinghouse and Guidelines International Network were searched to collect evidence-based guidelines on medication therapy for children with rheumatic fever. Methodological quality of included guidelines was assessed according to the AGREE Ⅱ instrument, and differences and similarities among recommendations were compared. Results Only one evidence-based clinical guideline from Australia was included. Among 6 domains which were rated using the AGREE Ⅱ instrument, "scope and purpose", "stakeholder involvement", "rigor of development", "clarity and presentation" and "applicability" were scored more than 50%; while "editorial independence" was scored less than 50%. Conclusion The included guideline is of relatively high quality; however, its application among Chinese population still has limitations. Thus, the development of national guidelines is urgently needed.

Citation: LIURu-ming, LIXiao-su, WANGLu-jie, ZHANGJun, ZHANGLing-li, LIYou-ping, LIUDan. Evidence-based Guidelines on Medication Therapy for Children with Rheumatic Fever: A Systematic Review. Chinese Journal of Evidence-Based Medicine, 2015, 15(1): 23-27. doi: 10.7507/1672-2531.20150007 Copy

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