Evidence-based Clinical Guidelines on Medication Therapy for Juvenile Idiopathic Arthritis: A Systematic Review_Chinese Journal of Evidence-Based Medicine

Authors：

 LIXiao-su ¹ , LIURu-ming ¹ , WANGLu-jie ¹ , ZHANGJun ¹ , ZHANGLing-li ^2,3 ,  LIYou-ping ⁴ , SONGJie ^2,3

1. Clinical Pharmacy Department, First Affiliated Hospital of Kunming Medical University, Kunming 650032, China;
2. Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
3. Evidence-based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, China;
4. Chinese Evidence-based Medicine Center, West China Hospital, Sichuan University, Chengdu 610041, China;

Corresponding author：

LIYou-ping, Email: zhangjunyang@126.com

Keywords：

Children; Juvenile idiopathic arthritis; Evidence-based guideline; Systematic review

DOI：

10.7507/1672-2531.20150027

Video：

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Objective To systematically assess the quality of evidence-based clinical guidelines on the treatment of children with juvenile idiopathic arthritis and to compare the differences and similarities between recommendations, so as to provide references for clinical application. Methods Databases such as the TRIP, PubMed, CNKI, VIP, WanFang Data, CBM, U.S National Guideline Clearinghouse and Guidelines International Network were searched to collect evidencebased guidelines on medication therapy for children with juvenile idiopathic arthritis. Methodological quality of included guidelines was assessed according to the AGREE Ⅲ instrument, and differences and similarities among recommendations were compared. Results Two evidence-based clinical guidelines from Australia and China were included. Among 6 domains of the Australian guideline which were rated using AGREE Ⅲ instrument, "scope and purpose", "stakeholder involvement", "rigor of development", "clarity and presentation", "applicability" and "editorial independence" were scored more than 50%. As for Chinese guideline, "scope and purpose", "stakeholder involvement", "rigor of development", "clarity and presentation" and "editorial independence" was all scored more than 50%, but "applicability" was scored less than 50%. Conclusion The included guidelines are of high quality and strongly recommended, but the recommendations might exist limitation for Chinese children. Thus, the development of relevant Chinese evidence-based guidelines are urgently needed.

Citation： LIXiao-su, LIURu-ming, WANGLu-jie, ZHANGJun, ZHANGLing-li, LIYou-ping, SONGJie. Evidence-based Clinical Guidelines on Medication Therapy for Juvenile Idiopathic Arthritis: A Systematic Review. Chinese Journal of Evidence-Based Medicine, 2015, 15(2): 152-158. doi: 10.7507/1672-2531.20150027 Copy

1.	安云飞, 赵晓东. 幼年特发性关节炎发病机制及进展. 中国医药指南, 2008, 6(12):46-48.
2.	《中华儿科杂志》编辑委员会, 中华医学会儿科学分会免疫学组. 幼年特发性关节炎(多/少关节型)诊疗建议. 中华儿科杂志,2012, 50(1):20-26.
3.	National Health and Medical Research Council. Clinical guideline for the diagnosis and management of juvenile idiopathic arthritis. 2009:43P.
4.	AGREE Next Steps Consortium. The AGREE Ⅲ Instrument, 2011. Available at:http://www.agreetrust.org.
5.	Burls A. AGREE Ⅲ-improving the quality of clinical care. Lancet, 2010, 376(9747):1128-1129.
6.	Zadvinskis IM, Grudell BA. Clinical practice guideline appraisal using the AGREE instrument:renal screening. Clin Nurse Spec, 2010, 24(4):209-214.
7.	Field MJ, Lohr KN. Guidelines for clinical practice:from development to use. Washington:National Academy Press, 1992.
8.	张伶俐, 李幼平, 张川, 等. 中国儿童临床指南现状分析及循证临床指南评价. 中国循证医学杂志, 2011, 11(9):991-999.
9.	杨克虎, 陈耀龙, 李幼平, 等. 中国能否应对指南挑战? 中国循证医学杂志, 2013, 13(6):621-623.
10.	李永柏. 幼年特发性关节炎(多/少关节型)诊疗建议解读. 2011年全国儿科风湿性疾病诊治专题研讨会论文汇编, 2011:55-62.
11.	屠志强, 蔡宇波, 曹兰芳. 2011年美国风湿病学会关于幼年特发性关节炎的治疗建议. 实用儿科临床杂志, 2011, 26(21):1689-1692.
12.	Vincenzi B, Napolitano A, Santini D, et al. Evidence-based guidelines:improving AGREEment on consistence evaluation. Journal of Bone Oncology, 2012, 1(1):30-34.
13.	韦当, 王小琴, 吴琼芳, 等. 2011年中国临床实践指南质量评价. 中国循证医学杂志, 2013, 13(6):760-763.

1. 安云飞, 赵晓东. 幼年特发性关节炎发病机制及进展. 中国医药指南, 2008, 6(12):46-48.
2. 《中华儿科杂志》编辑委员会, 中华医学会儿科学分会免疫学组. 幼年特发性关节炎(多/少关节型)诊疗建议. 中华儿科杂志,2012, 50(1):20-26.
3. National Health and Medical Research Council. Clinical guideline for the diagnosis and management of juvenile idiopathic arthritis. 2009:43P.
4. AGREE Next Steps Consortium. The AGREE Ⅲ Instrument, 2011. Available at:http://www.agreetrust.org.
5. Burls A. AGREE Ⅲ-improving the quality of clinical care. Lancet, 2010, 376(9747):1128-1129.
6. Zadvinskis IM, Grudell BA. Clinical practice guideline appraisal using the AGREE instrument:renal screening. Clin Nurse Spec, 2010, 24(4):209-214.
7. Field MJ, Lohr KN. Guidelines for clinical practice:from development to use. Washington:National Academy Press, 1992.
8. 张伶俐, 李幼平, 张川, 等. 中国儿童临床指南现状分析及循证临床指南评价. 中国循证医学杂志, 2011, 11(9):991-999.
9. 杨克虎, 陈耀龙, 李幼平, 等. 中国能否应对指南挑战? 中国循证医学杂志, 2013, 13(6):621-623.
10. 李永柏. 幼年特发性关节炎(多/少关节型)诊疗建议解读. 2011年全国儿科风湿性疾病诊治专题研讨会论文汇编, 2011:55-62.
11. 屠志强, 蔡宇波, 曹兰芳. 2011年美国风湿病学会关于幼年特发性关节炎的治疗建议. 实用儿科临床杂志, 2011, 26(21):1689-1692.
12. Vincenzi B, Napolitano A, Santini D, et al. Evidence-based guidelines:improving AGREEment on consistence evaluation. Journal of Bone Oncology, 2012, 1(1):30-34.
13. 韦当, 王小琴, 吴琼芳, 等. 2011年中国临床实践指南质量评价. 中国循证医学杂志, 2013, 13(6):760-763.

Chinese Journal of Evidence-Based Medicine

Evidence-based Clinical Guidelines on Medication Therapy for Juvenile Idiopathic Arthritis: A Systematic Review

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