Implementation of Meta-analysis for Effect Combination of Regression Coefficient in R Software with metafor Package_Chinese Journal of Evidence-Based Medicine

Authors：

 ZHANGYun-quan ,  MALu , FENGRen-jie , ZHUYao-hui , LICun-lu

Department of Epidemiology and Health Statistics, School of Public Health, Wuhan University, Wuhan 430071, China;

Corresponding author：

MALu, Email: malu@whu.edu.cn

Keywords：

Meta-analysis; R software; metafor package; Regression coefficient

DOI：

10.7507/1672-2531.20150062

Video：

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Objective To introduce the method of meta-analysis for effect combination of regression coefficient conducted with the metafor package in R software. Methods By using the data of a published meta-analysis as an example, the detailed process of meta-analysis for regression coefficient was presented with metafor package in R. Results The results of meta-analysis conducted with metaphor package in R were the same as the published literature. Conclusion As a completely free open source software for statistical analysis, R can conduct meta-analysis for effect combination of regression coefficient flexibly and precisely, and should be expanded in the future meta-analysis.

Citation： ZHANGYun-quan, MALu, FENGRen-jie, ZHUYao-hui, LICun-lu. Implementation of Meta-analysis for Effect Combination of Regression Coefficient in R Software with metafor Package. Chinese Journal of Evidence-Based Medicine, 2015, 15(3): 367-372. doi: 10.7507/1672-2531.20150062 Copy

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6.	董圣杰, 曾宪涛, 郭毅. R 软件 Metafor 程序包在 Meta 分析中的应用. 中国循证医学杂志, 2012, 12(9):1141-1147.
7.	Stieb DM, Chen L, Eshoul M, et al. Ambient air pollution, birth weight and preterm birth:a systematic review and meta-analysis. Environ Res, 2012, 117:100-111.
8.	石修权, 王增珍. Egger's test 与 Begg's test 的功效差异比较与原因分析. 华中科技大学学报:医学版, 2009, 38(1):91-93.
9.	Hayashino Y, Noguchi Y, Fukui T. Systematic evaluation and comparison of statistical tests for publication bias. J Epidemiol, 2005, 15(6):235-243.

1. Glass GV. Primary, secondary, and meta-analysis of research. Educ Res, 1976, 3-8.
2. 曾宪涛, 冷卫东, 李胜, 等. 如何正确理解及使用GRADE系统. 中国循证医学杂志, 2011, 11(9):985-990.
3. 曾宪涛, 冷卫东, 郭毅, 等. Meta分析系列之一:Meta 分析的类型. 中国循证心血管医学杂志, 2012, 4(1):3-5.
4. 曾宪涛, 田国祥, 董圣杰. Meta 分析系列之二:Meta 分析的软件. 中国循证心血管医学杂志, 2012, 4(2):89-91.
5. Viechtbauer W. Conducting meta-analyses in R with the metafor package. J Stat Softw, 2010, 36(3):1-48.
6. 董圣杰, 曾宪涛, 郭毅. R 软件 Metafor 程序包在 Meta 分析中的应用. 中国循证医学杂志, 2012, 12(9):1141-1147.
7. Stieb DM, Chen L, Eshoul M, et al. Ambient air pollution, birth weight and preterm birth:a systematic review and meta-analysis. Environ Res, 2012, 117:100-111.
8. 石修权, 王增珍. Egger's test 与 Begg's test 的功效差异比较与原因分析. 华中科技大学学报:医学版, 2009, 38(1):91-93.
9. Hayashino Y, Noguchi Y, Fukui T. Systematic evaluation and comparison of statistical tests for publication bias. J Epidemiol, 2005, 15(6):235-243.

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