CHENKuang-yang 1,2,3 # , QULi-na 1,2,4 # , HUFang 1,2,4 , ZHANGYi-Heng 1,2,3 , YANGJing-jing 1,2,4 , BAIXi 1,2,4 , MABin 1,2
  • 1. Evidence Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou 730000, China;
  • 2. Key Laboratory of Evidence Based Medicine and Knowledge Translation of Gansu Province, Lanzhou 730000, China;
  • 3. The First Clinical Medical College of Lanzhou University, Lanzhou 730000, China;
  • 4. The Second Clinical Medical College of Lanzhou University, Lanzhou 730000, China;
MABin, Email: mab@lzu.edu.cn
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Objective To provide a reference for developing search strategy of systematic reviews/meta-analyses (SRs/MAs) of animal researches (ARs) in future, we investigated and analyzed the search strategy of SRs/MAs of ARs at home and abroad. Methods Ovid-MEDLINE, Ovid-EMbase, Ovid-BIOSIS previews, CBM, CNKI, VIP and WanFang Data were searched from inception to January 2015, to collect SRs/MAs of ARs that related to medicine. No limitation in species. Two reviewers independently screened literature, extracted basic characteristics, databases and other sources searched, characteristics of reported search strategy of included studies. Result A total of 181 SRs/MAs of ARs were finally included. Less than 30% SRs/MAs searched more than three databases, 65.7% reported supplementary retrieval. 86.2% (156/181) SRs/MAs reported search terms, but only 12 reported search strategy; the search terms of 33 studies included specific name of animal, 27 studies used "animal/experimental model/", 20 studies used "limit to animal". 71.3% SRs/MAs reported specific time limitation of searching, 44.2% reported whether limited language, 23.8% of them limited language, and more of these limited to English. Conclusion At present, there are still some problems in SRs/MAs of ARs at home and abroad when choice database, search terms and search strategy, so we advise that:1) It's necessary to choice typical databases as many as possible according to search field; 2) Using specific animal's name and (or) "animal" as one of search terms, and using "limit to animal" according to characteristic of different databases; 3) The reporting of search strategy of SRs/MAs of ARs should include search sources, time limitation, language limitation, limitation of inclusion type, search terms and complete search strategy, besides, reporting knowledge of reviewers is also necessary; 4) To improve transparency and clarity of SRs/MAs of ARs, some related journals should introduce "reporting complete search strategy" in their instruction for authors.

Citation: CHENKuang-yang, QULi-na, HUFang, ZHANGYi-Heng, YANGJing-jing, BAIXi, MABin. The Search Strategy of Systematic Review/Meta-analysis of Animal Research: A Survey. Chinese Journal of Evidence-Based Medicine, 2016, 16(3): 348-353. doi: 10.7507/1672-2531.20160054 Copy

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