Evidence-based Chinese medicine: theory, research, and practice_Chinese Journal of Evidence-Based Medicine

Authors：

ZHANG Xiaoyu ¹ , CHEN Shiqi ¹ , LI Chengyu ¹ , TIAN Guihua ¹ , ZHAO Chen ² , QIU Ruijin ¹ , HU Jiayuan ¹ , ZHENG Rui ¹ , SUN Yang ¹ , LI Min ¹ , CHEN Yaolong ³ , SUN Xin ⁴ , LI Bo ⁵ , ZHANG Honglai ⁶ ,  BIAN Zhaoxiang ² ,  SHANG Hongcai ^1,6

1. Key Laboratory of Chinese Internal Medicine of Ministry of Education, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing, 100700, P.R.China;
2. School of Chinese Medicine, Hong Kong Baptist University, Hongkong, 999077, P.R.China;
3. Evidence-Based Medicine Center, School of Basic Medical Sciences Lanzhou University/Chinese GRADE Center, Lanzhou, 730000, P.R. China;
4. Chinese Evidence-Based Medicine Center, West China Hospital, Sichuan University, Chengdu, 610041, P.R. China;
5. Beijing Hospital of Traditional Chinese Medicine, Capital Medical University/Beijing Institute of traditional Chinese Medicine, Beijing, 100010, P.R. China;
6. Guangzhou University of Chinese Medicine, Guangzhou, 510006, P.R. China;

Corresponding author：

BIAN Zhaoxiang, Email: bianzxiang@gmail.com; SHANG Hongcai, Email: shanghongcai@foxmail.com

Keywords：

Evidence-based Chinese medicine; Concept; Narrative evidence-based medicine; Population-based; Individual-based

DOI：

10.7507/1672-2531.201707007

Video：

Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables Video References Cited by

Evidence-based Chinese medicine is a relatively new discipline which applies the concepts and methods of evidence-based medicine (EBM) to the clinical research and practice of Chinese medicine. It is not only a branch of EBM but also a natural product of the development of Chinese medicine. This paper introduces the theoretical concepts of evidence-based Chinese medicine and reviews the process of its development. It then elucidates the main characteristics of evidence-based Chinese medicine, emphasizes its holistic approach, prescription-syndrome relationship, and its human-centered approach. Research contents and status quo are also summarized to point out the challenges of the production and application of evidence. Finally, we innovatively indicate further research directions on combining individual-based research with population-based research and developing narrative EBM.

Citation： ZHANG Xiaoyu, CHEN Shiqi, LI Chengyu, TIAN Guihua, ZHAO Chen, QIU Ruijin, HU Jiayuan, ZHENG Rui, SUN Yang, LI Min, CHEN Yaolong, SUN Xin, LI Bo, ZHANG Honglai, BIAN Zhaoxiang, SHANG Hongcai. Evidence-based Chinese medicine: theory, research, and practice. Chinese Journal of Evidence-Based Medicine, 2018, 18(1): 86-91. doi: 10.7507/1672-2531.201707007 Copy

1.	Sackett DL, Rosenberg WM, Gray JA, et al. Evidence based medicine: what it is and what it isn't. BMJ, 1996, 312(7023): 71-72.
2.	WHO/EDM/TRM/2002.1. WHO Traditional Medicine Strategy. Available at: http://www.who.int/medicines/publications/ traditional/policy/en/.
3.	陈可冀, 宋军. 循证医学的提出对中西医结合的启发. 中国中西医结合杂志, 1999, 19(11): 643-644.
4.	李幼平. 循证医学(第一版). 北京: 人民卫生出版社, 2014. 342.
5.	王忠, 高颖, 王阶, 等. 中风病痰热腑实证的表型组学研究思路. 世界科学技术: 中医药现代化, 2015, 17(12): 2423-2429.
6.	刘建平. 循证医学方法与中医疗效评价. 首都医科大学学报, 2007, 28(2): 212-215.
7.	杨秋莉, 王永炎. 叙事医学与中医学的人文关怀. 现代中医临床, 2015, 22(2): 1-3.
8.	Liu ZS, Liu Y, Xu HF, et al. Effect of electroacupuncture on urinary leakage among women with stress urinary incontinence: a randomized clinical trial. JAMA, 2017, 317(24): 2493-2501.
9.	Li F, Harmer P, Fitzgerald K, et al. Tai chi and postural stability in patients with Parkinson's disease. N Engl J Med, 2012, 366(6): 511-519.
10.	王正品, 信云霞, 陈钟, 等. 循证医学在现代中药临床再评价中的应用. 中华中医药杂志, 2015, 30(7): 2259-2261.
11.	马彬. 中医药临床研究方法与报告质量研究. 兰州: 兰州大学, 2013.
12.	张晓雨, 李敏, 邱瑞瑾, 等. 系统评价方法在中成药上市后再研究评价中的应用误区及反思. 中国中西医结合杂志, 2017, 37(8): 996-999.
13.	汪受传, 虞舜, 赵霞, 等. 循证性中医临床诊疗指南研究的现状与策略. 中华中医药杂志, 2012, 27(11): 2759-2763.
14.	李幼平, 吴泰相, 刘关键, 等. 中国循证医学中心促进中医药现代化的策略. 中国循证医学杂志, 2007, 7(3): 159-161.
15.	Cheng CW, Wu TX, Shang HC, et al. CONSORT extension for Chinese herbal medicine formulas 2017: recommendations, explanation, and elaboration. Ann Intern Med, 2017, 167(2): 112-121.
16.	刘保延, 翁维良, 谢雁鸣, 等. 中西医结合治疗 SARS 临床研究. 医学研究杂志, 2006, 19(5): 5-7.
17.	Li X, Zhang J, Huang J, et al. A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the effects of qili qiangxin capsules in patients with chronic heart failure. J Am Coll Cardiol, 2013, 62(12): 1065.
18.	张淑萍. 芪参益气滴丸对心肌梗死二级预防的临床试验——中医药临床疗效循证评价模式、方法及关键技术. 中国科技成果, 2012, 13(4): 58.
19.	国家进步奖一等奖——" IgA肾病中西医结合证治规律与诊疗关键技术的创研及应用”. Available at: http://www.most.gov.cn/ztzl/ gjkxjsjldh/jldh2016/jldh16hjxmjj/201701/t20170105_130156.htm.
20.	赵晨, 刘智, 商洪才. 中医临床疗效评价差异化策略的提出——个体化研究方法学元素初探. 世界中医药, 2017(6): 1221-1225.
21.	Zhai J, Cao H, Ming R, et al. Reporting of core items in hierarchical Bayesian analysis for aggregating N-of-1 trials to estimate population treatment effects is suboptimal. J Clin Epidemiol, 2016, 76: 99-107.
22.	李江, 翟静波, 商洪才, 等. 单病例随机对照试验的起源与发展. 中国循证医学杂志, 2017, 17(2): 235-238.
23.	商洪才, 李幼平, 张伯礼, 等. 中医药临床疗效个体化评价方法初探——循证目标成就量表法的提出. 中国循证医学杂志, 2007, 7(7): 537-541.
24.	Li B, Gao H Y, Gao R, et al. Joint development of evidence-based medical record by doctors and patients through integrated Chinese and western medicine on digestive system diseases. Chin J Integr Med, 2016, 22(2): 83-87.

1. Sackett DL, Rosenberg WM, Gray JA, et al. Evidence based medicine: what it is and what it isn't. BMJ, 1996, 312(7023): 71-72.
2. WHO/EDM/TRM/2002.1. WHO Traditional Medicine Strategy. Available at: http://www.who.int/medicines/publications/ traditional/policy/en/.
3. 陈可冀, 宋军. 循证医学的提出对中西医结合的启发. 中国中西医结合杂志, 1999, 19(11): 643-644.
4. 李幼平. 循证医学(第一版). 北京: 人民卫生出版社, 2014. 342.
5. 王忠, 高颖, 王阶, 等. 中风病痰热腑实证的表型组学研究思路. 世界科学技术: 中医药现代化, 2015, 17(12): 2423-2429.
6. 刘建平. 循证医学方法与中医疗效评价. 首都医科大学学报, 2007, 28(2): 212-215.
7. 杨秋莉, 王永炎. 叙事医学与中医学的人文关怀. 现代中医临床, 2015, 22(2): 1-3.
8. Liu ZS, Liu Y, Xu HF, et al. Effect of electroacupuncture on urinary leakage among women with stress urinary incontinence: a randomized clinical trial. JAMA, 2017, 317(24): 2493-2501.
9. Li F, Harmer P, Fitzgerald K, et al. Tai chi and postural stability in patients with Parkinson's disease. N Engl J Med, 2012, 366(6): 511-519.
10. 王正品, 信云霞, 陈钟, 等. 循证医学在现代中药临床再评价中的应用. 中华中医药杂志, 2015, 30(7): 2259-2261.
11. 马彬. 中医药临床研究方法与报告质量研究. 兰州: 兰州大学, 2013.
12. 张晓雨, 李敏, 邱瑞瑾, 等. 系统评价方法在中成药上市后再研究评价中的应用误区及反思. 中国中西医结合杂志, 2017, 37(8): 996-999.
13. 汪受传, 虞舜, 赵霞, 等. 循证性中医临床诊疗指南研究的现状与策略. 中华中医药杂志, 2012, 27(11): 2759-2763.
14. 李幼平, 吴泰相, 刘关键, 等. 中国循证医学中心促进中医药现代化的策略. 中国循证医学杂志, 2007, 7(3): 159-161.
15. Cheng CW, Wu TX, Shang HC, et al. CONSORT extension for Chinese herbal medicine formulas 2017: recommendations, explanation, and elaboration. Ann Intern Med, 2017, 167(2): 112-121.
16. 刘保延, 翁维良, 谢雁鸣, 等. 中西医结合治疗 SARS 临床研究. 医学研究杂志, 2006, 19(5): 5-7.
17. Li X, Zhang J, Huang J, et al. A multicenter, randomized, double-blind, parallel-group, placebo-controlled study of the effects of qili qiangxin capsules in patients with chronic heart failure. J Am Coll Cardiol, 2013, 62(12): 1065.
18. 张淑萍. 芪参益气滴丸对心肌梗死二级预防的临床试验——中医药临床疗效循证评价模式、方法及关键技术. 中国科技成果, 2012, 13(4): 58.
19. 国家进步奖一等奖——" IgA肾病中西医结合证治规律与诊疗关键技术的创研及应用”. Available at: http://www.most.gov.cn/ztzl/ gjkxjsjldh/jldh2016/jldh16hjxmjj/201701/t20170105_130156.htm.
20. 赵晨, 刘智, 商洪才. 中医临床疗效评价差异化策略的提出——个体化研究方法学元素初探. 世界中医药, 2017(6): 1221-1225.
21. Zhai J, Cao H, Ming R, et al. Reporting of core items in hierarchical Bayesian analysis for aggregating N-of-1 trials to estimate population treatment effects is suboptimal. J Clin Epidemiol, 2016, 76: 99-107.
22. 李江, 翟静波, 商洪才, 等. 单病例随机对照试验的起源与发展. 中国循证医学杂志, 2017, 17(2): 235-238.
23. 商洪才, 李幼平, 张伯礼, 等. 中医药临床疗效个体化评价方法初探——循证目标成就量表法的提出. 中国循证医学杂志, 2007, 7(7): 537-541.
24. Li B, Gao H Y, Gao R, et al. Joint development of evidence-based medical record by doctors and patients through integrated Chinese and western medicine on digestive system diseases. Chin J Integr Med, 2016, 22(2): 83-87.

Chinese Journal of Evidence-Based Medicine

Evidence-based Chinese medicine: theory, research, and practice

Abstract Full text Figures/Tables Video References Cited by

Previous Article

Next Article

Format

Content