TANG Xiaoyu 1,2,3 , LI Han 1,2,4 , SUN Dili 1,2,3 , NIU Jialan 1,2,3 , ZHU Min 1,2,4 , LI Jing 1,2,4 , BIAN Tianyue 1,2,4 , KUANG Xinying 5 , GENG Jinsong 6 , ZHAO Fei 7 , LIU Yali 1,2 , LIU Xia 8 , MA Bin 1,2
  • 1. Evidence-Based Medicine Center, School of Basic Medical Sciences, Lanzhou University, Lanzhou, 730000, P.R.China;
  • 2. Key Laboratory of Evidence-Based Medicine and Knowledge Translation of Gansu Province, Lanzhou, 730000, P.R.China;
  • 3. The Second Clinical Medical College of Lanzhou University, Lanzhou, 73000, P.R.China;
  • 4. The First Clinical Medical College of Lanzhou University, Lanzhou, 73000, P.R.China;
  • 5. The Chinese University of Hong Kong Jockey Club School of Public Health, Hongkong, 999077, P.R.China;
  • 6. Department of Medical Informatics, Medical School of Nantong University, Nantong, 226001, P.R.China;
  • 7. School of Medicine, Northwest Minzu University, Lanzhou, 730030, P.R.China;
  • 8. Key Laboratory of Preclinical Study for New Drugs of Gansu Province, Department of Pharmacology, School of Basic Medical Science, Lanzhou University, Lanzhou, 730000, P.R.China;
MA Bin, Email: mab@lzu.edu.cn
Animal experiment; Systematic review; Meta-analysis; Search strategy; Introduction
10.7507/1672-2531.201709056
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ObjectivesTo introduce the formulating methods and implementing steps of search strategy of systematic reviews (SRs)/meta-analysis (MAs) of animal experiments, so as to provide a reference for domestic related researchers, and promote the development and implementation of high quality SRs/MAs of animal experiments in China. MethodsPubMed, EMbase and CNKI databases were searched online to retrieve studies on the search strategy of SRs/ MAs of animal experiments from inception to October 2017. A descriptive analysis was then conducted using the evidence-based medicine theory and method.ResultsA total of 5 studies were included. The 5 basic steps on how to design and carry out comprehensive search strategies to identify potentially relevant animal experiments on a specific research question were as follow: 1) Formulate research question; 2) Identify appropriate databases and sources of studies; 3) Transform research question into search strategy; 4) Collect search results and remove duplicates; 5) Identify potentially relevant papers. The report of search strategy needs to state its search method and search results clearly.ConclusionThese 5 steps can provide an effective method, which will assist researchers in performing a comprehensive literature search.

Citation： TANG Xiaoyu, LI Han, SUN Dili, NIU Jialan, ZHU Min, LI Jing, BIAN Tianyue, KUANG Xinying, GENG Jinsong, ZHAO Fei, LIU Yali, LIU Xia, MA Bin. How to develop the search strategy of systematic reviews/meta-analysis of animal researches: an introduction. Chinese Journal of Evidence-Based Medicine, 2018, 18(5): 515-520. doi: 10.7507/1672-2531.201709056 Copy