Prevalence of senile pruritus in Chinese population: a meta-analysis_Chinese Journal of Evidence-Based Medicine

Authors：

CHEN Shi ,  GAO Jing , BAI Dingxi , HE Lianci , ZHONG Yizhu , BAO Xinru , WU Qiao , WU Chenxi

School of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, P.R.China;

Corresponding author：

GAO Jing, Email: 729012934@qq.com

Keywords：

China; Senile pruritus; Epidemiological characteristics; Prevalence; Meta-analysis; Systematic review; Cross-sectional study

DOI：

10.7507/1672-2531.201910023

Video：

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Objectives To systematically review the prevalence of senile pruritus (SP) in Chinese population.Methods PubMed, EMbase, CENTRAL, CINAHL, CBM, CNKI, WanFang Data and VIP databases were electronically searched to collect cross-sectional studies on the prevalence of SP in Chinese population from inception to May 2019. Two reviewers independently screened literature, extracted data and assessed risk of bias of included studies, then, meta-analysis was performed by Stata 12.0 software.Results A total of 11 studies involving 13 398 patients were included. The results of meta-analysis showed that, the overall prevalence of SP was 31.0% (95%CI 18.0% to 44.0%). Subgroup analysis showed that the prevalence rate of male was 34.9% (95%CI 18.6% to 88.5%). The prevalence rates of SP among 60, 70, 80 and 90 age groups were 20.0% (95%CI 14.2% to 25.7%), 48.4% (95%CI 21.5% to 75.3%), 53% (95%CI 12.4% to 93.5%), and 58.5% (95%CI 22.4% to 94.6%), respectively. The prevalence rates of SP in community, hospital and cadre relaxation club were 33.4% (95%CI 31.3% to 35.6%), 40.4% (95%CI 22% to 58.7%), and 14.4% (95%CI 1.1% to 27.7%), respectively. The prevalence rates of SP in southern China and northern China were 26.7% (95%CI 18.7% to 34.7%) and 36.8% (95%CI 21.8% to 51.7%), respectively.Conclusions The overall prevalence rate of SP in the Chinese population is high. The prevalence rates of SP among ages, regions and research sites are different.

Citation： CHEN Shi, GAO Jing, BAI Dingxi, HE Lianci, ZHONG Yizhu, BAO Xinru, WU Qiao, WU Chenxi. Prevalence of senile pruritus in Chinese population: a meta-analysis. Chinese Journal of Evidence-Based Medicine, 2020, 20(5): 562-567. doi: 10.7507/1672-2531.201910023 Copy

1.	张倩, 王洪志, 高静, 等. 中医调欲疗法对老年性皮肤瘙痒症患者睡眠质量的影响. 中华护理杂志, 2017, 52(2): 161-165.
2.	张倩, 高静, 史兰辉, 等. 中医情志调欲法对老年皮肤瘙痒症患者症状及生活质量的影响. 中国老年学杂志, 2016, 36(19): 4897-4899.
3.	曾宪涛, 刘慧, 陈曦, 等. Meta分析系列之四: 观察性研究的质量评价工具. 中国循证心血管医学杂志, 2012, 4(4): 297-299.
4.	熊风, 赖玉清, 涂嘉欣, 等. 中国老年人群睡眠障碍流行特征的Meta分析. 中国循证医学杂志, 2019, 19(4): 28-33.
5.	张丽. 太原市中老年干部皮肤病调查. 太原: 山西医科大学, 2012.
6.	陈祖辉, 莫海霞, 冼俊芳, 等. 广州某社区老年人皮肤病现状及其影响因素. 暨南大学学报(自然科学与医学版), 2015, 36(1): 73-76.
7.	葛蒙梁, 谢志宏, 张春玲, 等. 122例单纯性老年瘙痒症相关因素的病例对照研究. 中华流行病学杂志, 2006, 27(7): 627-629.
8.	侯秀芳, 张力军. 老年皮肤病196例影响因素调查分析. 陕西医学杂志, 2016, 45(11): 1559-1560.
9.	李丹, 窦娜, 马素慧, 等. 老年皮肤瘙痒症的危险因素分析. 中国全科医学, 2013, 16(26): 3062-3065.
10.	李琳, 王婷, 刘晓峥. 老年性皮肤瘙痒症的危险因素分析及健康指导. 西南军医, 2014, (5): 591-592.
11.	倪鹤梁, 柯晓燕, 钱明强, 等. 上海市两家养老机构老年瘙痒性皮肤病发病情况分析. 中国中西医结合皮肤性病学杂志, 2012, 11(3): 25-26.
12.	武娜, 张东玲. 老年性皮肤瘙痒症的调查及病因分析. 中国疗养医学, 2014, 23(4): 90-91.
13.	薛树旗. 太钢职工老年性皮肤病调查. 中国皮肤性病学杂志, 2008, 22(7): 32-33.
14.	杨洁, 赵华, 周勇, 等. 410名男性老年瘙瘁症患者危险因素病例对照研究. 现代预防医学, 2009, 36(10): 1820-1822.
15.	Tseng HW, Ger LP, Liang CK, et al. High prevalence of cutaneous manifestations in the elderly with diabetes mellitus: an institution-based cross-sectional study in Taiwan. J Eur Acad Dermatol Venereol, 2015, 29(8): 1631-1635.
16.	Thaipisuttikul Y. Pruritic skin diseases in the elderly. J Dermatol, 1998, 25(3): 153-157.
17.	Caretti KL, Mehregan DR, Mehregan DA. A survey of self-reported skin disease in the elderly African-American population. Int J Dermatol, 2015, 54(9): 1034-1038.
18.	Valdes-Rodriguez R, Mollanazar NK, González-Muro J, et al. Itch prevalence and characteristics in a Hispanic geriatric population: a comprehensive study using a standardized itch questionnaire. Acta Derm Venereol, 2015, 95(4): 417-421.
19.	Reszke R, Białynicki-Birula R, Lindner K, et al. Itch in elderly people: a cross-sectional study. Acta Derm Venereol, 2019, 99(11): 1016-1021.
20.	唐桦. AQP3在不同年龄段正常人皮肤组织及角质形成细胞, 成纤维细胞中的表达. 长沙: 中南大学, 2008.
21.	张子衿, 祝均, 孟宏, 等. 老年性瘙痒症发病机制研究进展. 中国老年学杂志, 2018, 38(18): 251-253.
22.	Fang D, Elly C, Gao B, et al. Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation. Nat Immunol, 2002, 3(3): 281-287.
23.	Bretscher PA. On the mechanism determining the TH1/TH2 phenotype of an immune response, and its pertinence to strategies for the prevention, and treatment, of certain infectious diseases. Scand J Immunol, 2014, 79(6): 361-376.
24.	李元文, 李楠. 皮肤瘙痒症中医诊治专家共识(北京地区). 北京中医药, 2017, (9): 777-779.
25.	Reszke R, Pełka D, Walasek A, et al. Skin disorders in elderly subjects. Int J Dermatol, 2015, 54(9): e332-e338.

1. 张倩, 王洪志, 高静, 等. 中医调欲疗法对老年性皮肤瘙痒症患者睡眠质量的影响. 中华护理杂志, 2017, 52(2): 161-165.
2. 张倩, 高静, 史兰辉, 等. 中医情志调欲法对老年皮肤瘙痒症患者症状及生活质量的影响. 中国老年学杂志, 2016, 36(19): 4897-4899.
3. 曾宪涛, 刘慧, 陈曦, 等. Meta分析系列之四: 观察性研究的质量评价工具. 中国循证心血管医学杂志, 2012, 4(4): 297-299.
4. 熊风, 赖玉清, 涂嘉欣, 等. 中国老年人群睡眠障碍流行特征的Meta分析. 中国循证医学杂志, 2019, 19(4): 28-33.
5. 张丽. 太原市中老年干部皮肤病调查. 太原: 山西医科大学, 2012.
6. 陈祖辉, 莫海霞, 冼俊芳, 等. 广州某社区老年人皮肤病现状及其影响因素. 暨南大学学报(自然科学与医学版), 2015, 36(1): 73-76.
7. 葛蒙梁, 谢志宏, 张春玲, 等. 122例单纯性老年瘙痒症相关因素的病例对照研究. 中华流行病学杂志, 2006, 27(7): 627-629.
8. 侯秀芳, 张力军. 老年皮肤病196例影响因素调查分析. 陕西医学杂志, 2016, 45(11): 1559-1560.
9. 李丹, 窦娜, 马素慧, 等. 老年皮肤瘙痒症的危险因素分析. 中国全科医学, 2013, 16(26): 3062-3065.
10. 李琳, 王婷, 刘晓峥. 老年性皮肤瘙痒症的危险因素分析及健康指导. 西南军医, 2014, (5): 591-592.
11. 倪鹤梁, 柯晓燕, 钱明强, 等. 上海市两家养老机构老年瘙痒性皮肤病发病情况分析. 中国中西医结合皮肤性病学杂志, 2012, 11(3): 25-26.
12. 武娜, 张东玲. 老年性皮肤瘙痒症的调查及病因分析. 中国疗养医学, 2014, 23(4): 90-91.
13. 薛树旗. 太钢职工老年性皮肤病调查. 中国皮肤性病学杂志, 2008, 22(7): 32-33.
14. 杨洁, 赵华, 周勇, 等. 410名男性老年瘙瘁症患者危险因素病例对照研究. 现代预防医学, 2009, 36(10): 1820-1822.
15. Tseng HW, Ger LP, Liang CK, et al. High prevalence of cutaneous manifestations in the elderly with diabetes mellitus: an institution-based cross-sectional study in Taiwan. J Eur Acad Dermatol Venereol, 2015, 29(8): 1631-1635.
16. Thaipisuttikul Y. Pruritic skin diseases in the elderly. J Dermatol, 1998, 25(3): 153-157.
17. Caretti KL, Mehregan DR, Mehregan DA. A survey of self-reported skin disease in the elderly African-American population. Int J Dermatol, 2015, 54(9): 1034-1038.
18. Valdes-Rodriguez R, Mollanazar NK, González-Muro J, et al. Itch prevalence and characteristics in a Hispanic geriatric population: a comprehensive study using a standardized itch questionnaire. Acta Derm Venereol, 2015, 95(4): 417-421.
19. Reszke R, Białynicki-Birula R, Lindner K, et al. Itch in elderly people: a cross-sectional study. Acta Derm Venereol, 2019, 99(11): 1016-1021.
20. 唐桦. AQP3在不同年龄段正常人皮肤组织及角质形成细胞, 成纤维细胞中的表达. 长沙: 中南大学, 2008.
21. 张子衿, 祝均, 孟宏, 等. 老年性瘙痒症发病机制研究进展. 中国老年学杂志, 2018, 38(18): 251-253.
22. Fang D, Elly C, Gao B, et al. Dysregulation of T lymphocyte function in itchy mice: a role for Itch in TH2 differentiation. Nat Immunol, 2002, 3(3): 281-287.
23. Bretscher PA. On the mechanism determining the TH1/TH2 phenotype of an immune response, and its pertinence to strategies for the prevention, and treatment, of certain infectious diseases. Scand J Immunol, 2014, 79(6): 361-376.
24. 李元文, 李楠. 皮肤瘙痒症中医诊治专家共识(北京地区). 北京中医药, 2017, (9): 777-779.
25. Reszke R, Pełka D, Walasek A, et al. Skin disorders in elderly subjects. Int J Dermatol, 2015, 54(9): e332-e338.

Chinese Journal of Evidence-Based Medicine

Prevalence of senile pruritus in Chinese population: a meta-analysis

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