Methods of developing evaluation indicators of rational drug use in children based on diseases or medicines_Chinese Journal of Evidence-Based Medicine

Authors：

CHEN Zhe ^1,2,3,4,5 , WANG Qiqiong ^1,2,3,4 , ZENG Linan ^1,2,3,4 , HUANG Liang ^1,2,3,4 , ZOU Kun ^1,2,3,4 , LI Hailong ^1,2,3,4 , JIA Zhijun ^1,2,3,4,5 , CHENG Guo ^4,6,7 ,  ZHANG Lingli ^1,2,3,4

1. Department of Pharmacy, West China Second University Hospital, Sichuan University, Chengdu 610041, P. R. China;
2. Evidence-Based Pharmacy Center, West China Second University Hospital, Sichuan University, Chengdu 610041, P. R. China;
3. NMPA Key Laboratory for Technical Research on Drug Products in vitro and in vivo Correlation, Chengdu 610041, P. R. China;
4. Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu 610041, P. R. China;
5. West China School of Pharmacy, Sichuan University, Chengdu 610041, P. R. China;
6. Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, P. R. China;
7. Molecular Translational Medicine Laboratory, Translational Medicine Center of Sichuan University, Chengdu 610041, P. R. China;

Corresponding author：

ZHANG Lingli, Email: zhanglingli@scu.edu.cn

Keywords：

Children; Rational drug use; Evaluation; Indicators; Methodology

DOI：

10.7507/1672-2531.202209126

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Rational drug use is a global concern. As one of the highest risk groups for drug use, children's rational drug use has always been concerned. Based on the previous research results of the research group, we developed evaluation indicator systems for assessing rational drug use to treat community-acquired pneumonia and primary nephrotic syndrome in children and proton pump inhibitors in pediatric intensive care units and finished empirical research. This study further summarizes and expounds the construction ideas of rational drug use evaluation indicators for children based on diseases or drugs, and provides a reference for constructing children's rational drug use evaluation indicators.

Citation： CHEN Zhe, WANG Qiqiong, ZENG Linan, HUANG Liang, ZOU Kun, LI Hailong, JIA Zhijun, CHENG Guo, ZHANG Lingli. Methods of developing evaluation indicators of rational drug use in children based on diseases or medicines. Chinese Journal of Evidence-Based Medicine, 2023, 23(6): 691-694. doi: 10.7507/1672-2531.202209126 Copy

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4.	World health organization. Children’s medicines: a situational analysis 2011.
5.	Song J, Zhang L, Li Y, et al. Indicators for assessing quality of drug use: a systematic literature review. J Evid Based Med, 2017, 10(3): 222-232.
6.	World health organization. The pursuit of responsible use of medicines: sharing and learning from country experiences.
7.	傅孟元, 王壮飞, 马元元, 等. 国际合理用药评价指标研究概述. 中国药事, 2018, 32(4): 538-545.
8.	张亚琳, 廖晓阳, 陈正勇. 合理用药评价指标研究进展. 中国药业, 2020, 29(16): 9-11.
9.	Li W, Zeng L, Li J, et al. Development of indicators for assessing rational drug use to treat community-acquired pneumonia in children in hospitals and clinics: a modified Delphi study. Medicine (Baltimore), 2017, 96(51): e9308.
10.	Lin M, Huang L, Zeng L, et al. An empirical study on the index system of rational drug use in children with primary nephrotic syndrome: a cross-sectional study. Medicine (Baltimore), 2020, 99(32): e21564.
11.	Ni X, Lin M, Li J, et al. Development of an evaluation indicator system for the rational use of proton pump inhibitors in pediatric intensive care units: an application of Delphi method. Medicine (Baltimore), 2021, 100(24): e26327.
12.	陶洋旭, 李建军. 医疗共识制订方法: 德尔菲法和名义小组法. 国际眼科纵览, 2021, 45(5): 369-373.
13.	Lin M, Zeng L, Huang L, et al. Application of Delphi method and analytic hierarchy process to establish indicator system for evaluation of rational drug use in children with primary nephrotic syndrome: observational study. Medicine (Baltimore), 2020, 99(19): e19949.

1. World Health Organization. World health statistics 2012.
2. World health organization. The global burden of disease 2004 update 2008.
3. Bryce J, Boschi-Pinto C, Shibuya K, et al. WHO estimates of the causes of death in children. Lancet, 2005, 365(9465): 1147-1152.
4. World health organization. Children’s medicines: a situational analysis 2011.
5. Song J, Zhang L, Li Y, et al. Indicators for assessing quality of drug use: a systematic literature review. J Evid Based Med, 2017, 10(3): 222-232.
6. World health organization. The pursuit of responsible use of medicines: sharing and learning from country experiences.
7. 傅孟元, 王壮飞, 马元元, 等. 国际合理用药评价指标研究概述. 中国药事, 2018, 32(4): 538-545.
8. 张亚琳, 廖晓阳, 陈正勇. 合理用药评价指标研究进展. 中国药业, 2020, 29(16): 9-11.
9. Li W, Zeng L, Li J, et al. Development of indicators for assessing rational drug use to treat community-acquired pneumonia in children in hospitals and clinics: a modified Delphi study. Medicine (Baltimore), 2017, 96(51): e9308.
10. Lin M, Huang L, Zeng L, et al. An empirical study on the index system of rational drug use in children with primary nephrotic syndrome: a cross-sectional study. Medicine (Baltimore), 2020, 99(32): e21564.
11. Ni X, Lin M, Li J, et al. Development of an evaluation indicator system for the rational use of proton pump inhibitors in pediatric intensive care units: an application of Delphi method. Medicine (Baltimore), 2021, 100(24): e26327.
12. 陶洋旭, 李建军. 医疗共识制订方法: 德尔菲法和名义小组法. 国际眼科纵览, 2021, 45(5): 369-373.
13. Lin M, Zeng L, Huang L, et al. Application of Delphi method and analytic hierarchy process to establish indicator system for evaluation of rational drug use in children with primary nephrotic syndrome: observational study. Medicine (Baltimore), 2020, 99(19): e19949.

Chinese Journal of Evidence-Based Medicine

Methods of developing evaluation indicators of rational drug use in children based on diseases or medicines

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