• Research Institute of Translational Medicine, Central Hospital Affiliated to Shandong First Medical University, Jinan 250013, China;
WANG Guangxin, Email: 2280887385@qq.com; SU Guohai, Email: suguohai65@163.com
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Objective To analyze the clinical characteristics, risk factors, treatment and prognosis of epilepsy secondary to cerebral infarction.Methods The clinical data of 109 patients with epilepsy secondary to cerebral infarction admitted to the Affiliated Central Hospital of Shandong First Medical University from October 2018 to February 2021 were retrospectively analyzed, including the location of cerebral infarction, seizure type, seizure time and antiepileptic treatment.Results 3 426 patients with cerebral infarction were treated in the same period, and the incidence of epilepsy secondary to cerebral infarction was 3.18%. Among 109 patients with epilepsy secondary to cerebral infarction, 71 were male and 38 were female, the average age was (67.42 ± 28.58) years. Time of seizure after cerebral infarction: 67 cases (61.47%) were early onset epilepsy and 42 cases (42.47%) were late onset epilepsy. The infarct site: 63.30% (69 /109) in cortex, 11.93% (13/109) in subcortical area, and 24.77% (27/109) in lacunar infarction secondary epilepsy. 5 cases died, the fatality rate was 1.59%, of which 4 patients died of early onset epilepsy, status epilepticus, and 1 patient died of late onset epilepsy due to acute cerebral infarction.Conclusions In patients with epilepsy secondary to cerebral infarction, the cortex is the most common site of infarction; focal seizures are more than comprehensive seizures; status epilepticus often indicates poor prognosis, so timely antiepileptic treatment should be given to improve the prognosis.

Citation: YANG Yang, WANG Guangxin, LIU Peng, SU Guohai. Clinical analysis of 109 cases of epilepsy secondary to cerebral infarction. Journal of Epilepsy, 2021, 7(4): 314-317. doi: 10.7507/2096-0247.20210050 Copy

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