眶内霉菌感染一例并文献复习_West China Medical Journal

Authors：

周娟 ¹ , 张勤 ¹ , 张丽娟 ² ,  邹晓毅 ¹

Corresponding author：

邹晓毅, Email: 54522247@qq.com

Keywords：

眶内感染; 霉菌

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【摘要】　目的　报道眶内霉菌感染一例。　方法　 2011年3月4日收治1例眶内霉菌感染患者，结合文献分析其临床特点及诊治方法。　结果　患者为47岁女性，有霉菌性鼻窦炎病史，右眼肿胀、视物模糊。经抗真菌治疗，病情稳定出院；后多次复发入院，且出现肝肾功能损害。经抗真菌、保肝、保肾、对症治疗，病情稳定出院。　结论　眶内霉菌感染多系鼻窦炎扩散而来，易复发，疗程较长，治疗过程中应监测肝肾功能。

Citation： 周娟,张勤,张丽娟,邹晓毅. 眶内霉菌感染一例并文献复习. West China Medical Journal, 2011, 26(12): 1878-1879. doi: Copy

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1. 　Türel O. Newer antifungal agents[J]. Expert rev anti infect ther, 2011, 9(3): 325-338.
2. 　Rapidis AD. Orbitomaxillary mucormycosis (zygomycosis) and the surgical approach to treatment:perspectives from a maxillofacial surgeon[J]. Clin Microbiol Infect, 2009,15(Suppl 5): 98-102.
3. 　Spellberg B, Fu Y, Edwards JE Jr, et al. Combination therapy with amphotericin B lipid complex and caspofungin acetate of disseminated zygomycosis in diabetic ketoacidotic mice[J]. Antimicrob Agents Chemother, 2005, 49(2): 830-832.
4. 　Walsh T, Anaissie E, Denning DW, et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America[J]. Clin Infect Dis, 2008, 46(3): 327-360.
5. 　Riddell J 4th, Comer GM, Kauffman CA. Treatment of endogenous fungal endophthalmitis: focus on new antifungal agents[J]. Clin Infect Dis, 2011, 52(5): 648-653.
6. 　Herbrecht R, Denning DW, Patterson TF, et al. Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis[J]. N Engl J Med, 2002, 347(6): 408-415.
7. 　Boucher HW, Groll AH, Chiou CC, et al. Newer systemic antifungal agents: pharmacokinetics, safety and efficacy[J]. Drugs, 2004, 64(18): 1997-2020.
8. 　Pascual A, Calandra T, Bolay S, et al. Voriconazole therapeutic drug monitoring in patients with invasive mycoses improves efficacy and safety outcomes[J].Clin Infect Dis, 2008, 46(2): 201-211.

West China Medical Journal

眶内霉菌感染一例并文献复习

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