Clinical Analysis of 13 Patients with Cervical Cancer Associated with Pregnancy_West China Medical Journal

Authors：

CHAI Dan , ZHENG Ai , ZHANG Jian , et al.

Department of Obstetrics and Gynecology，West China Second University Hospital，Sichuan University，Chengdu 610041，China;

Corresponding author：

Keywords：

妊娠相关性宫颈癌; 细胞学; 首次产检; 原位癌; 密切随诊; 新辅助化疗; 

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目的:探讨妊娠相关性宫颈癌的早期诊断、治疗和预后。方法:结合文献回顾分析我院2000年至2007年收治的13例妊娠相关性宫颈癌的诊治经过和预后。结果:妊娠相关性宫颈癌分化程度低，癌灶体积大，早期盆腔淋巴结转移率高，产褥期宫颈癌预后差。结论:宫颈细胞学检查应列为首次产检常规项目；妊娠期宫颈原位癌在密切随诊前提下可暂不予处理，待分娩后6~8周活检确认病变性质后，再采取相应治疗措施；新辅助化疗同样可为晚期别的妊娠相关性宫颈癌争取手术时机。

Citation： CHAI Dan,ZHENG Ai,ZHANG Jian,et al.. Clinical Analysis of 13 Patients with Cervical Cancer Associated with Pregnancy. West China Medical Journal, 2009, 24(1): 108-110. doi: Copy

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5.	Economos D，Perez VN，Delke I，et al.Abnormal cervical cytology in pregnancy:A 17year experience[J].Obstet Gynecol，1993，81:915-918..
6.	Nguyen C，Montz FJ，Bristow RE.Management of stage Ⅰ cervical cancer in pregnancy[J].Obstetr Gynecol Surv，2000，55（10）:633-643..
7.	Ackermann S，Gehrsitz C，Mehlhorn G，et al.Management and course of histologically verified cervical.Carcinoma in situ during pregnancy[J].Acta Obstet Gynecol Scand，2006，85（9）:1134-1137..
8.	Dargent D，Brun JL，Roy M，et al.Pregnancies following radical trachelectomyfor invasive cervical cancer[J].Gynecol Oncol，1994，52:105..
9.	Roy M，Plante M.Pregnancies after radical vaginal trachelectomy for early stage cervical cancer[J].Am J Obstet Gynecol，1998，179:1491-1496.
10.	Burnett AF.Radical trachelectomy with laparoscopic lymphadenectomy:review of oncologic and obstetrical out comes[J].Curr Opin Obstet Gynecol，2006，18(1):8-13..
11.	Sood AK，Sorosky JI.Invasive cervical cancer complicated pregnancy.How to manage the dilemma[J].Obstet Gynecol Clin North Am，1998，25:343-352..
12.	Nagell JR，Higgins RV.Clinical invasive carcinoma of cervix，malcolm coppleson[J].Gynecol Oncol，1992，46:664..

1. 张国楠.宫颈上皮内瘤变的处理指南[J].实用妇产科杂志，2004，20（2）:72..
2. Sood AK，Sorosky JI，Mayr N，et al.Cervical cancer diagnosed shortly after pregnancy:prognostic variables and delivery routes[J].Obstet Gynecol，2000，95（6 Pt 1）:832-838..
3. Centers for Disease Control and Prevention.Sexually Transmitted Diseases Treatment Guidelines，2002[J]. MMWR，2002，51:5..
4. 陈俊雅，杨慧峡，李克敏，等.妊娠合并宫颈病变的分析[J].中华围产医学杂志，2004，7（6）:337-338..
5. Economos D，Perez VN，Delke I，et al.Abnormal cervical cytology in pregnancy:A 17year experience[J].Obstet Gynecol，1993，81:915-918..
6. Nguyen C，Montz FJ，Bristow RE.Management of stage Ⅰ cervical cancer in pregnancy[J].Obstetr Gynecol Surv，2000，55（10）:633-643..
7. Ackermann S，Gehrsitz C，Mehlhorn G，et al.Management and course of histologically verified cervical.Carcinoma in situ during pregnancy[J].Acta Obstet Gynecol Scand，2006，85（9）:1134-1137..
8. Dargent D，Brun JL，Roy M，et al.Pregnancies following radical trachelectomyfor invasive cervical cancer[J].Gynecol Oncol，1994，52:105..
9. Roy M，Plante M.Pregnancies after radical vaginal trachelectomy for early stage cervical cancer[J].Am J Obstet Gynecol，1998，179:1491-1496.
10. Burnett AF.Radical trachelectomy with laparoscopic lymphadenectomy:review of oncologic and obstetrical out comes[J].Curr Opin Obstet Gynecol，2006，18(1):8-13..
11. Sood AK，Sorosky JI.Invasive cervical cancer complicated pregnancy.How to manage the dilemma[J].Obstet Gynecol Clin North Am，1998，25:343-352..
12. Nagell JR，Higgins RV.Clinical invasive carcinoma of cervix，malcolm coppleson[J].Gynecol Oncol，1992，46:664..

West China Medical Journal

Clinical Analysis of 13 Patients with Cervical Cancer Associated with Pregnancy

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