Investigation the Influence of Sichuan Wenchuan Earthquake on Patients of Rheumatoid Arthritis_West China Medical Journal

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Department of Rheumatology and Immunology，The Center Hospital of Mianyang City，Mianyang Sichuan 621000，China;

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Keywords：

地震; 类风湿关节炎

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目的:本文研究5·12四川汶川大地震造成停药、居住条件恶劣、创伤后应激障碍（posttraumatic stress disorder，PTSD）、是否并发感染、地震破坏烈度等多种因素对类风湿关节炎（RA）患者的影响。方法:对58例确诊为RA的重灾区（北川、平武、江油、安县）地震前病情稳定患者震后一月进行血沉（ESR）和C反应蛋白（CRP）测定，同时评估患者关节肿胀、关节压痛、晨僵情况，了解患者是否病情活动，分析地震造成停药、居住条件恶劣、PTSD、并发感染及地震破坏烈度等多种因素对RA的影响。采用fisher确切概率法，分析地震破坏烈度与疾病活动是否有相关性，采用SPSS12.0软件对地震可能影响RA患者病情活动的其它相关因素进行Logistic回归分析。结果:58例患者中34例RA患者出现病情活动。fisher确切概率法分析显示:上述四县患者疾病活动构成比差别无统计学意义。病情活动者中62%患者停药；85%患者居住条件恶劣；59%患者患有PTSD；35%患者并发感染。Logistic回归分析发现停药、居住条件恶劣、PTSD及并发感染与RA患者病情活动相关（P均小于0.05）。结论：本研究中涉及的四个县RA患者疾病活动构成比差异无显著性，地震造成的停药、居住条件恶劣、PTSD、并发感染可使一部分RA患者病情活动。

Citation： YANG Jing,DONG Jianlin,ZOU Jinmei,et al.. Investigation the Influence of Sichuan Wenchuan Earthquake on Patients of Rheumatoid Arthritis. West China Medical Journal, 2009, 24(1): 120-122. doi: Copy

1.	Grady KE，Reisine ST，Fifield J，et al.The impact of Hurricane Hugo and the San Francisco earthquake on a sample of people with rheumatoid arthritis[J].Arthritis Care Res，1991，4（2）:106-110..
2.	American Psychiatric Association:Diagnostic and Statistical Manual of Mental Disorders，4th ed （DSM-IV）[M].Washington，DC，APA，1994..
3.	Drane D，Berry G.，BieriD，et al.Association between external weather conditions and pain and stiffness in women with rheumatoid arthritis[J].J Rheumatol，1997，24:1309-1316..
4.	Strusberg I，Mendelberg RC，Serra HA，et al.Influence of weather conditions on rheumatic pain[J].J Rheumatol，2002，29（2）:335-338..
5.	Lepore L，Agosti E，Pennesi M，et al.Longterm remission induced by measles infection and followed by immunosuppressive therapy in a case of refractory juvenile rheumatoid arthritis[J]，1988，10（2）:191-193..
6.	Saulsbury FT.Remission of juvenile rheumatoid arthritis with varicella infection[J].J Rheumatol，1999，26（7）:1606-1608..
7.	Bateman HE，Kirou KA，Paget SA，et al.Remission of juvenile rheumatoid arthritis after infection with parvovirus B19[J].J Rheumatol，1999，26（11）:2482-2484..
8.	Remission of rheumatoid arthritis after acute disseminated varicellazoster infection[J].Clin Rheumatol，2007，26（5）:779-780..
9.	Motivala SJ，Khanna D，FitzGerald J，et al.Stress activation of cellular markers of inflammation in rheumatoid arthritis:protective effects of tumor necrosis factor α antagonists[J].Arthritis Rheum.
10.	Stojanovich L，Marisavljevich D.Stress as a trigger of autoimmune disease[J].Autoimmun Rev，2008，7（3）:209-213..
11.	HaghShenas H，Goodarzi MA，Farajpoor M，et al.Posttraumatic stress disorder among survivors of Bam earthquake 40 days after the event[J].East Mediterr Health J，2006，12:118-125..
12.	Montazeri A，Baradaran H，Omidvari S，et al.Psychological distress among Bam earthquake survivors in Iran:a populationbased study[J].BMC Public Health，2005，5:4..

1. Grady KE，Reisine ST，Fifield J，et al.The impact of Hurricane Hugo and the San Francisco earthquake on a sample of people with rheumatoid arthritis[J].Arthritis Care Res，1991，4（2）:106-110..
2. American Psychiatric Association:Diagnostic and Statistical Manual of Mental Disorders，4th ed （DSM-IV）[M].Washington，DC，APA，1994..
3. Drane D，Berry G.，BieriD，et al.Association between external weather conditions and pain and stiffness in women with rheumatoid arthritis[J].J Rheumatol，1997，24:1309-1316..
4. Strusberg I，Mendelberg RC，Serra HA，et al.Influence of weather conditions on rheumatic pain[J].J Rheumatol，2002，29（2）:335-338..
5. Lepore L，Agosti E，Pennesi M，et al.Longterm remission induced by measles infection and followed by immunosuppressive therapy in a case of refractory juvenile rheumatoid arthritis[J]，1988，10（2）:191-193..
6. Saulsbury FT.Remission of juvenile rheumatoid arthritis with varicella infection[J].J Rheumatol，1999，26（7）:1606-1608..
7. Bateman HE，Kirou KA，Paget SA，et al.Remission of juvenile rheumatoid arthritis after infection with parvovirus B19[J].J Rheumatol，1999，26（11）:2482-2484..
8. Remission of rheumatoid arthritis after acute disseminated varicellazoster infection[J].Clin Rheumatol，2007，26（5）:779-780..
9. Motivala SJ，Khanna D，FitzGerald J，et al.Stress activation of cellular markers of inflammation in rheumatoid arthritis:protective effects of tumor necrosis factor α antagonists[J].Arthritis Rheum.
10. Stojanovich L，Marisavljevich D.Stress as a trigger of autoimmune disease[J].Autoimmun Rev，2008，7（3）:209-213..
11. HaghShenas H，Goodarzi MA，Farajpoor M，et al.Posttraumatic stress disorder among survivors of Bam earthquake 40 days after the event[J].East Mediterr Health J，2006，12:118-125..
12. Montazeri A，Baradaran H，Omidvari S，et al.Psychological distress among Bam earthquake survivors in Iran:a populationbased study[J].BMC Public Health，2005，5:4..

West China Medical Journal

Investigation the Influence of Sichuan Wenchuan Earthquake on Patients of Rheumatoid Arthritis

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