目的:调查6个短串联重复(short tandem repeat,STR)基因座在中国四川成都汉族人群中的基因频率分布。方法:应用四色荧光标记引物复合扩增技术对260名成都汉族无关个体的血样6个STR基因座进行多态性研究。结果:在四川成都汉族人群中6个STR基因座个体识别机率PD为0.796~0.913,杂合度HO为0.627~0.796,多态信息含量PIC为0.57~0.75。6个STR基因座PD总值为0.999 995 97。所有基因座经卡方检验符合Hard-Weinberg平衡。结论:上述6个STR基因座在成都汉族人群中等位基因分布较好,个体识别率高,适合法医个体识别和亲子鉴定。
Citation:
MeiLangQuCuo,YING Binwu,FAN Hong. Genetic Polymorphism of 6 Short Tandem Repeat Loci in Han Population in Chengdu. West China Medical Journal, 2009, 24(1): 143-145. doi:
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