目的:观测外周造血干/祖细胞采集术对造血干/祖细胞采集的临床效果。方法:对14例患者及11例健康捐献者进行外周造血干/祖细胞采集术52例次,观测采集前后外周血WBC、RBC、Hb、Hct、Plt,采集后CD34+细胞、CFU-GM量,以及不良反应。结果:经过1~3次采集,采集量达到造血干/祖细胞移植所需量,不良反应轻微。结论:外周血干/祖细胞采集具有处理量大,副作用小,安全高效等优点。
Citation:
GAN Maozhou,ZHOU Biao,ZHANG Jinlin. Clinical Observation of 52 Peripheral Blood Stem/Progenitor Cells Harvesting. West China Medical Journal, 2008, 23(1): 50-51. doi:
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Hillyer CD,Tiegerman KO,Berkman EM.A commercially available culture medium compares favorably to laboratory medium(LM)for assay of peripheral blood colony forming units(CFU)[J].Bone Marrow Transplant,1991,7(6):493.
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陈会友,朱康儿,江朝富,等.大容量白细胞单采术采集外周血干/祖细胞[J].中国输血杂志,2002,15(5):331-332.
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梁辉,常君,郑伟敏,等.血细胞分离机在小儿血液病治疗中的应用[J].中华儿科杂志,1999,37(10):641-642.
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- 1. Hillyer CD,Tiegerman KO,Berkman EM.A commercially available culture medium compares favorably to laboratory medium(LM)for assay of peripheral blood colony forming units(CFU)[J].Bone Marrow Transplant,1991,7(6):493.
- 2. 陈会友,朱康儿,江朝富,等.大容量白细胞单采术采集外周血干/祖细胞[J].中国输血杂志,2002,15(5):331-332.
- 3. 梁辉,常君,郑伟敏,等.血细胞分离机在小儿血液病治疗中的应用[J].中华儿科杂志,1999,37(10):641-642.