Microsurgical Treatment of Pineal Region Tumors_West China Medical Journal

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四川大学华西医院神经外科，四川成都 610041;

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Keywords：

松果体区占位; 脑肿瘤; 显微外科手术

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目的：研究比较松果体区肿瘤的显微外科手术切除不同手术入路及其优缺点。方法：回顾分析收治的48例松果体区肿瘤患者的手术情况及术后表现，并进行分析。结果：48例患者中，经枕小脑幕切开（Poppen）入路31例，幕下小脑上（Krause）入路8例，经胼胝体-穹窿间入路6例，经胼胝体后部（Dandy）入路2例，颞部侧脑室三角部入路1例。肿瘤全切除40例，次全切除5例，大部分切除3例。8例未全切者及病理证实为恶性的病变术后行放疗和（或）化疗，5例术后并发脑积水行分流术，偏盲1例，死亡2例,随访6个月～6年，KPS大于80分者约43例。结论：松果体区肿瘤的手术治疗效果较好，全切率高、死亡率低，合理的入路及体位，娴熟的显微外科手术技巧是手术成功的关键，Poppen入路和Krause入路是符合微创理念的理想入路。

Citation： CAI Bowen,YOU Chao,ZHOU Liangxue,et al.. Microsurgical Treatment of Pineal Region Tumors. West China Medical Journal, 2008, 23(1): 65-66. doi: Copy

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1. 罗世棋.儿童颅内肿瘤[M].北京：人民卫生出版社,1992.
2. Matsutani M，Sano K，Takakura K，et a1.Primary intracranial germ cell tumors:a clinical analysis of 153 histologically verified cases[J].J Neurosurg，1997，86：446-457.
3. Sawamura Y,de Tribolet N,Ishii N,et al.Management of primary intracranialgerminoomas:diagnostic surgery orradical resection[J]?Neurosurgery,1997,87:262-266.
4. Sawamura Y,Kato T,Ikeda J,et al.Teratomas of the central nevous system:treatment considerations based on 34 cases[J].J Neurosurg,1998,89:728-737.
5. Fukui M,Natori Y,Matsushima T,et al.Operative approaches to the pineal region tumors[J].Childs Nerv Syst,1998,14(1-2):49-52.
6. Schmidek HH.Management of pineal region neoplasms.In：Shimidek HH，Sweet WH,eds.Operative neurosurgical techniques[M].4th ed.Philadelphia：WB Saunders，2000:891-894.
7. Blakeley JO,Grossman SA.Management of pineal region tumors[J].Curr Treat Options Oncol,2006,7(6):505-516.

West China Medical Journal

Microsurgical Treatment of Pineal Region Tumors

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