• Department of Gastrointestinal Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China;
ZHANG Bo, Email: hxwcwk@126.com
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Objective  To investigate the differences of postoperative quality of life (QOL) between proximal gas-
trectomy (PG) and total gastrectomy (TG) in patients with adenocarcinoma of esophagogastric junction (AEG).
Methods  Eighty five patients with AEG (Siewert type Ⅱ or Ⅲ) who were underwent PG or TG surgery between Jan. 2011 and
Mar. 2012 at West China Hospital of Sichuan University were enrolled, to measure the QOL by using the Chinese
version of quality of life questionnaire core-30 (QLQ-C30) and the site-specific module for gastric cancer (QLQ-STO22)
which were drawed up by the European Organization for Research and Treatment of Cancer (EORTC) in 12 months after
operation.
Results  There were no any difference of clinicopathological features between patients in 2 groups (P>0.05),
such as age, gender, and so on. The scores of eating restriction, diarrhea, and dyspnea in PG group were lower than those of TG group (P<0.05), but scores of reflux and taste change were higher (P<0.05), no other significant differ-
ence was found between the patients of 2 groups (P>0.05).
Conclusion  Both of PG+gastric tube reconstruction and TG+Roux-en-Y anastomosis in treatment of patients with Siewert type Ⅱ or Ⅲ AEG may lead to complications, but patients who underwent former surgery have better situation in eating restriction, diarrhea, and dyspnea, and patients who underwent later surgery have better situation in reflux and taste change.

Citation: HEN Chaoyong,YANG Hongxin,ZHANG Bo,CHEN Haining,CHEN Zhixin,CHEN Jiaping. Influence on Quality of Life after Proximal Gastrectomy and Total Gastrectomy for Adenocarcinoma of Esophago-gastric Junction. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2013, 20(12): 1381-1385. doi: Copy