Objective To explore the effect of endovascular treatment guided by ultrasonography combined with portosystemic shunts on the patients with Budd-Chiari Syndrome (BCS).
Methods The clinical data of 136 patients with BCS treated by balloon angioplasty and stent implantation guided by Doppler ultrasonography in our hospital from January 1995 to January 2011 were retrospectively analyzed.After balloon angioplasty,53 patients were treated by inferior vena cava (IVC) stent implantation and 31 patients with hepatic venous occlusion underwent portosystemic shunts (PSSs) at one week after endovascular treatment.The long-and short-term effects after treatment were studied.
Results After endovascular procedures,the IVC pressure of patients significantly decreased (P<0.01),while IVC diameter, flow velocity in the lesion,and right atrial pressure of patients showed significant increase(P<0.01).Slight heart dysfunction appeared in 13 cases of patients.After shunting,acute pancreatitis occurred in 3 cases, and 1 patient died of upper gastrointestinal hemorrhage on the 10 d after PSSs.Doppler ultrasonography for IVC and shunt vessels showed:the swollen liver and spleen lessened on 3d after endovascular procedures.The swollen liver lessened 2-7cm (mean 5.5cm),swollen spleen lessened 3-8cm (mean 5.8cm), and the time of ascites disappearance was 3-60d (mean 14d).All the patients were followed up for 1 month to 15 years with an average of 3 years.Restenosis of the distal part of stent was found in 1 patient in 2 years after operation, hepatic vein occlusion occurred in 1 case in 1 year after treatment,hepatocellular carcinoma occurred in 1 patient in 3 years after stent implantation,and 1 patient died of C type hepatitis after 1 year,and 5 out of 6 cases of patients with infertility had babies after 1 year.All patients had no stent migration or occlusion of shunts and the symptoms of portal hypertension were obviously relieved.
Conclusions Endovascular treatment guided by Doppler ultrasonography is a convenient,safe,and effective method for BCS.Portosystemic shunts are commended to patients with hepatic venous occlusions.The above mentioned methods provide a feasible and effective means for IVC stenosis and short segment occlusion with hepatic vein occlusion of BCS.
Citation: HAN Bing,HUANG Yingjun,ZHANG Hongguang,ZHOU Chenguang,JI Guohui,YANG Zheng,ZHANG Liang.. Study on The Effect of Endovascular Treatment Guided by Ultrasonography Combined with Portosystemic Shunts for Budd-Chiari Syndrome. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2012, 19(1): 72-76. doi: Copy