Analysis for Resent Follow-up Results of In-Stent Restenosis in Carotid Artery_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Authors：

ZHOU Bo ¹ , ZHU Ting ² , FU Weiguo ² , YAN Zhiping ¹

Department of Radiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China;

Corresponding author：

Keywords：

Carotid artery; Stent; Restenosis

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Objective　To find out the follow-up results of early in-stent restenosis (ISRS) and develop effective way to improve clinical treatment and precaution of restenosis. Methods　The data from a registry of 51 consecutive patients who underwent elective carotid artery angioplasty and stenting （CAS） at our institution between Jan. 2003 and Sept. 2005 were retrospectively reviewed. Complete data for 37 of these patients were available. All patients underwent duplex ultrasound scanning in follow-up period, which was used to determine the degree of restenosis. Results　CAS was performed in 37 patients， 8.1% (3/37) were women. Mean age was (70.5±5.9) years. Mean time of follow-up was (12.2±7.7) months. Sixteen (43.2%) caces of ISRS （ gt;30%） were found by color duplex ultrasound scanning， but only 1 (2.7%) ISRS was found gt;50%; 3 female patients had minor ISRS. Among all factors, female patients had higher incidence of ISRS than male (P=0.038); balloon-expanding after stenting and accompanying with other artherosclerosis of periphery vessel had correlation about ISRS （P=0.037, P=0.016）. Conclusion　The severe restenosis rate is acceptable. Female patients were more likely to have ISRS. Balloon-expanding maybe have effect on reducing incidence of ISRS and controlling artherosclerosis was helpful.

Citation： ZHOU Bo,ZHU Ting,FU Weiguo,YAN Zhiping. Analysis for Resent Follow-up Results of In-Stent Restenosis in Carotid Artery. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2006, 13(6): 662-664. doi: Copy

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14.	Chakhtoura EY, Hobson RW 2nd, Goldstein J, et al. In-stent restenosis after carotid angioplasty-stenting: incidence and management [J]. J Vasc Surg， 2001; 33(2)∶220.
15.	Zhou W, Lin PH, Bush RL, et al. Management of in-sent restenosis after carotid artery stenting in high-risk patients [J]. J Vasc Surg， 2006; 43(2)∶305.
16.	Setacci C, de Donato G, Setacci F, et al. In-stent restenosis after carotid angioplasty and stenting: a challenge for the vascular surgeon [J]. Eur J Vasc Endovasc Surg， 2005; 29(6)∶601.
17.	Choi HM, Hobson RW, Goldstein J, et al. Technical challenges in a program of carotid artery stenting [J]. J Vasc Surg， 2004; 40(4)∶746.
18.	Setacci C, de Donato G, Setacci F, et al. Surgical management of acute carotid thrombosis after carotid stenting: a report of three cases [J]. J Vasc Surg， 2005; 42(5)∶993.

1. 　Gonzalez A, Gonzalez-Marcos JR, Martinez E, et al. Safety and security of carotid artery stenting for severe stenosis with contralateral occlusion [J]. Cerebrovasc Dis， 2005; 20 Suppl 2∶123.
2. 　Yadav JS, Wholey MH, Kuntz RE, et al. Protected carotid-artery stenting versus endarterectomy in high-risk patients [J]. N Engl J Med， 2004; 351(15)∶1493.
3. 　Bergeron P, Roux M, Khanoyan P, et al.Long-term results of carotid stenting are competitive with surgery [J]. J Vasc Surg， 2005; 41(2)∶213.
4. 　Frericks H, Kievit J, van Baalen JM, et al. Carotid recurrent stenosis and risk of ipsilateral stroke: a systematic review of the literature [J]. Stroke， 1998; 29(1)∶244.
5. 　Moore WS, Kempczinski RF, Nelson JJ, et al. Recurrent carotid stenosis: results of the asymptomatic carotid atherosclerosis study [J]. Stroke， 1998; 29(10)∶2018.
6. 　Endovascular versus surgical treatment in patients with carotid stenosis in the Carotid and Vertebral Artery Transluminal Angioplasty Study (CAVATAS): a randomised trial [J]. Lancet， 2001; 357(9270)∶1729.
7. 　Lal BK, Hobson RW 2nd. Management of carotid restenosis [J]. J Cardiovasc Surg (Torino)， 2006; 47(2)∶153.
8. 　Powell RJ, Schermerhorn M, Nolan B, et al. Early results of carotid stent placement for treatment of extracranial carotid bifurcation occlusive disease [J]. J Vasc Surg， 2004; 39(6)∶1193.
9. 　Criado FJ, Lingelbach JM, Ledesma DF, et al. Carotid artery stenting in a vascular surgery practice [J]. J Vasc Surg， 2002; 35(3)∶430.
10. 　Henry M, Amor M, Klonaris C, et al. Angioplasty and stenting of the extracranial carotid arteries [J]. Tex Heart Inst J， 2000; 27(2)∶150.
11. 　Toma N, Matsushima S, Murao K, et al. Histopathological findings in a human carotid artery after stent implantation. Case report [J]. J Neurosurg， 2003; 98(1)∶199.
12. 　Willfort-Ehringer A, Ahmadi R, Gschwandtner ME, et al. Healing of carotid stents: a prospective duplex ultrasound study [J]. J Endovasc Ther， 2003; 10(3)∶636.
13. 　Cunningham EJ, Bond R, Mehta Z, et al. Long-term durability of carotid endarterectomy for symptomatic stenosis and risk factors for late postoperative stroke [J]. Stroke， 2002; 33(11)∶2658.
14. 　Chakhtoura EY, Hobson RW 2nd, Goldstein J, et al. In-stent restenosis after carotid angioplasty-stenting: incidence and management [J]. J Vasc Surg， 2001; 33(2)∶220.
15. 　 Zhou W, Lin PH, Bush RL, et al. Management of in-sent restenosis after carotid artery stenting in high-risk patients [J]. J Vasc Surg， 2006; 43(2)∶305.
16. 　Setacci C, de Donato G, Setacci F, et al. In-stent restenosis after carotid angioplasty and stenting: a challenge for the vascular surgeon [J]. Eur J Vasc Endovasc Surg， 2005; 29(6)∶601.
17. 　Choi HM, Hobson RW, Goldstein J, et al. Technical challenges in a program of carotid artery stenting [J]. J Vasc Surg， 2004; 40(4)∶746.
18. 　Setacci C, de Donato G, Setacci F, et al. Surgical management of acute carotid thrombosis after carotid stenting: a report of three cases [J]. J Vasc Surg， 2005; 42(5)∶993.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Analysis for Resent Follow-up Results of In-Stent Restenosis in Carotid Artery

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