1. |
Ganz T, Selsted ME, Szklarek D, et al. Defensins. Natural peptide antibiotics of human neutrophils [J]. J Clin Invest, 1985; 76(4)∶1427.
|
2. |
Rice WG, Ganz T, Kinkade JM Jr, et al. Defensinrich dense granules of human neutrophils [J]. Blood, 1987; 70(3)∶757.
|
3. |
Lehrer RI, Ganz T, Selsted ME. Defensins: endogenous antibiotic peptides of animal cells [J]. Cell, 1991; 64(2)∶229.
|
4. |
Ogata K, Linzer BA, Zuberi RI, et al. Activity of defensins from human neutrophilic granulocytes against Mycobacterium aviumMycobacterium intracellulare [J]. Infect Immun, 1992; 60(11)∶4720.
|
5. |
Gabay JE, Almeida RP. Antibiotic peptides and serine protease homologs in human polymorphonuclear leukocytes: defensins and azurocidin [J]. Curr Opin Immunol, 1993; 5(1)∶97.
|
6. |
Jones DE, Bevins CL. Paneth cells of the human small intestine express an antimicrobial peptide gene [J]. J Biol Chem, 1992; 267(32)∶23216.
|
7. |
Bevins CL, Jones DE, Dutra A, et al. Human enteric defensin genes: chromosomal map position and a model for possible evolutionary relationships [J]. Genomics, 1996; 31(1)∶95.
|
8. |
Ghosh D, Porter E, Shen B, et al. Paneth cell trypsin is the processing enzyme for human defensin5 [J]. Nat Immunol, 2002; 3(6)∶583.
|
9. |
Com E, Bourgeon F, Evrard B, et al. Expression of antimicrobial defensins in the male reproductive tract of rats, mice, and humans [J]. Biol Reprod, 2003; 68(1)∶95.
|
10. |
Porter EM, Poles MA, Lee JS, et al. Isolation of human intestinal defensins from ileal neobladder urine [J]. FEBS Lett, 1998; 434(3)∶272.
|
11. |
Martin E, Ganz T, Lehrer RI. Defensins and other endogenous peptide antibiotics of vertebrates [J]. J Leukoc Biol, 1995; 58(2)∶128.
|
12. |
Porter EM, Liu L, Oren A, et al. Localization of human intestinal defensin 5 in Paneth cell granules [J]. Infect Immun, 1997; 65(6)∶2389.
|
13. |
Porter EM, van Dam E, Valore EV, et al. Broadspectrum antimicrobial activity of human intestinal defensin 5 [J]. Infect Immun, 1997; 65(6)∶2396.
|
14. |
Lehrer RI, Barton A, Daher KA, et al. Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity [J]. J Clin Invest, 1989 ; 84(2)∶553.
|
15. |
Bevins CL, MartinPorter E, Ganz T. Defensins and innate host defence of the gastrointestinal tract [J]. Gut, 1999; 45(6)∶911.
|
16. |
Ouellette AJ, Satchell DP, Hsieh MM, et al. Characterization of luminal paneth cell alphadefensins in mouse small intestine. Attenuated antimicrobial activities of peptides with truncated amino termini [J]. J Biol Chem, 2000; 275(43)∶33969.
|
17. |
Ganz T. Microbiology: Gut defence [J]. Nature, 2003; 422(6931)∶478.
|
18. |
Linzmeier R, Ho CH, Hoang BV, et al. A 450kb contig of defensin genes on human chromosome 8p23 [J]. Gene, 1999; 233(1-2)∶205.
|
19. |
Ayabe T, Satchell DP, Wilson CL, et al. Secretion of microbicidal alphadefensins by intestinal Paneth cells in response to bacteria [J]. Nat Immunol, 2000; 1(2)∶113.
|
20. |
Wilson CL, Ouellette AJ, Satchell DP, et al. Regulation of intestinal alphadefensin activation by the metalloproteinase matrilysin in innate host defense [J]. Science, 1999; 286(5437)∶113.
|
21. |
Selsted ME, Miller SI, Henschen AH, et al. Enteric defensins: antibiotic peptide components of intestinal host defense [J]. J Cell Biol, 1992; 118(4)∶929.
|
22. |
Salzman NH, Ghosh D, Huttner KM, et al. Protection against enteric salmonellosis in transgenic mice expressing a human intestinal defensin [J]. Nature, 2003; 422(6931)∶522.
|
23. |
方文惠,姚永明, 施国志, 等. 肠源性防御素与肠道天然免疫 [J]. 解放军医学杂志, 2000; 25(6)∶463.
|
24. |
Schonwetter BS, Stolzenberg ED, Zasloff MA. Epithelial antibiotics induced at sites of inflammation [J]. Science, 1995; 267(5204)∶1645.
|
25. |
李全生, 张肇达, 陈晓理, 等. 实验性胰腺炎小鼠小肠隐凹素4mRNA表达变化的研究 [J]. 四川大学学报(医学版), 2003; 34(1)∶92.
|
26. |
Cunliffe RN, Rose FR, Keyte J, et al. Human defensin 5 is stored in precursor form in normal Paneth cells and is expressed by some villous epithelial cells and by metaplastic Paneth cells in the colon in inflammatory bowel disease [J]. Gut, 2001; 48(2)∶176.
|
27. |
Shirafuji Y, Tanabe H, Satchell DP, et al. Structural determinants of procryptdin recognition and cleavage by matrix metalloproteinase7 [J]. J Biol Chem, 2003; 278(10)∶7910.
|
28. |
Quayle AJ, Porter EM, Nussbaum AA, et al.. Gene expression, immunolocalization, and secretion of human defensin5 in human female reproductive tract [J]. Am J Pathol, 1998; 152(5)∶1247.
|
29. |
Diamond G, Bevins CL. betaDefensins: endogenous antibiotics of the innate host defense response [J]. Clin Immunol Immunopathol, 1998; 88(3)∶221.
|
30. |
Grandjean V, Vincent S, Martin L, et al.. Antimicrobial protection of the mouse testis: synthesis of defensins of the cryptdin family [J]. Biol Reprod, 1997; 57(5)∶1115.
|
31. |
Frye M, Bargon J, Dauletbaev N, et al.. Expression of human alphadefensin 5 (HD5) mRNA in nasal and bronchial epithelial cells [J]. J Clin Pathol, 2000; 53(10)∶770.
|