• Beijing Army General Hospital, Beijing 100700;
Colorectal cancer; Liver metastasis; Liposome; Endostatin; Therapy
Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables References Cited by

Objective  To investigate the influence of cationic liposomemediated endostatin gene on colorectal cancer liver metastasis.
Methods  Animal model for colorectal carcinoma liver metastasis were established. The plasmid expressing endostatin genelipofectAMINE were injected in vein. Results  After cationic liposomemediated endostatin gene were injected in vein, the incidence of liver metastasis and mean numbers of liver tumors were decreased, survival time of animal was significantly longer.
Conclusion  Intravenous injection of cationic liposomemediated endostatin gene can control the development of colorectal cancer liver metastasis effectively.

Citation： LUO Chengyu,ZHAO Danning,ZENG Sheng,et al.. The Influence of Cationic LiposomeMediated Endostatin Gene on Colorectal Carcinoma Liver Metastasis. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2002, 9(1): 23-25. doi: Copy