Early Effect Following the Resection of IlealCecum and Right HemicolonAn Experimental Study_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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Department of Pediatric Surgery, West China Hospital, Sichuan University, Chengdu 610041;

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Keywords：

Ilealcecum colon; Metabolism; Operation

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Objective To explore the early effect following resection of ilealcecum and right hemicolon. MethodsTwenty piglets were randomly divided into 2 groups, 10 in control group and experimental group respectively. The ilealcecum and right hemicolon for 50 cm each were resected in the experimental group. The two groups were fed the same food before and after the operation. Some indexes of two groups were monitored. Results①In the two groups, the body length change wasn’t significant (P gt;0.05); but the body weight had descended markly in experimental group, compared with control group, since 3 weeks after operation (P lt;0.05). ②In experimental group, the ileal bacteria were increased from 104-107/ml before operation to 109-1011/ml at 6 weeks after operation (P lt;0.05). ③The enterohepatic circulation of biliac acid was affected during the early phase after resection. ④In experimental group, the stool became diluted within 6 weeks after operation. ⑤In the two groups, the Vitamin B12 was waved slightly within 6 weeks after operation (P gt;0.05). The megaloblastic anemia was not appeared. ⑥The function of liver and the absorption of Na+, Cl-,K+ did not change significantly (P gt;0.05). Conclusion The ileocecum and right hemicolon are very important for digestion and absorption, it should be retained or the ileocecal valve should be reconstructed if possible.

Citation： XIANG Bo,WEI Fukang,LUO Qicheng,et al. Early Effect Following the Resection of IlealCecum and Right HemicolonAn Experimental Study. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2002, 9(2): 96-99. doi: Copy

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13.	Ben CJ, Shonfeld O, Goldwasser B, et al. Does the use of the ileocecal region in reconstrictive urology cause persistent diarrhea [J]. Eur Urol, 1995; 27(4)∶315.
14.	黄象谦, 于中麟主编. 胃肠道疾病治疗学 [M]. 第1版. 天津: 天津科学技术出版社, 1996∶619~624.
15.	Jimenez AC, Encinas GI, Ruiz MA, et al. Consequences of resecting the ileocecal union [J]. Cir Pediatr, 1990; 3(2)∶45.
16.	Tadashi L, Kohei H, Hideo K, et al. Ileocecal resection in neonates and infants: a followup study [J]. J Pediatr Surg, 1993; 28(1)∶110.

1. 魏鸿主编.医学实验动物学 [M]. 第1版.成都: 四川科学技术出版社, 1998∶206~207.
2. Banwell JG, Kistler LA, Giannella RA, et al. Small intestinal bacterial overgrowth syndrome [J]. Gastroenterology, 1981; 80(4)∶834.
3. Richardson JG, Griffen WO. Ileocecal valve substitutes as bacteriologic barriers [J]. Am J Surg, 1972; 123(3)∶149.
4. 叶任高主编. 内科学 [M].第5版.北京: 人民卫生出版社, 2001∶595~598.
5. Akerlund S, Delin K, Kock NG, et al. Renal function and upper urinary trace configuration following urinary diversion to a contient ileal reservior construction [J]. J Urol, 1989; 142(4)∶964.
6. Stein R, Lotz J, Fisch M, et al. Vitamin metabolism in patient with mainz pouch I: longterm follow up [J]. J Urol, 1997; 157(1)∶44.
7. 周爱儒主编. 生物化学 [M]. 第5版. 北京: 人民卫生出版社, 2001∶ 374~377.
8. Anderson H, Bosaeus I, Fasth S, et al. Determination of the fecal excretion of labelled bile salt after I.V administration of 14ccholic acid. An evaluation of the bile salt malabsorption before and after surgery in patients with Crohn’s disease [J]. Scand J Gastroenterol, 1978; 13（2）∶249.
9. Davies BW, Abel G, Puntis JW, et al. Limit ileal resection in infancy: the longterm consequences [J]. J Pediatr Surg, 1999; 34(4)∶583.
10. Iwanaka T, Hashizume K, Kawarosaki H, et al. A followup study in individuals subjected to ileocecal resection in infancy and childhood [J]. Minerva Pediatr, 1996; 48(9)∶365.
11. 李正，王练英.回盲部或右半结肠切除患者随访观察 [J]. 中华小儿外科杂志， 1993; 14(3)∶129.
12. Fallingborg J, Pedersen P, Jacobsen BA. Small intestinal transit time and intraluminal pH in ileocecal resected patients with Crohn’s disease [J]. Dig Dis Sci, 1998; 43(4)∶702.
13. Ben CJ, Shonfeld O, Goldwasser B, et al. Does the use of the ileocecal region in reconstrictive urology cause persistent diarrhea [J]. Eur Urol, 1995; 27(4)∶315.
14. 黄象谦, 于中麟主编. 胃肠道疾病治疗学 [M]. 第1版. 天津: 天津科学技术出版社, 1996∶619~624.
15. Jimenez AC, Encinas GI, Ruiz MA, et al. Consequences of resecting the ileocecal union [J]. Cir Pediatr, 1990; 3(2)∶45.
16. Tadashi L, Kohei H, Hideo K, et al. Ileocecal resection in neonates and infants: a followup study [J]. J Pediatr Surg, 1993; 28(1)∶110.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

Early Effect Following the Resection of IlealCecum and Right HemicolonAn Experimental Study

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