目的总结原发性甲状腺鳞癌的诊治经验。方法回顾分析我院1996~2001年收治的12例原发性甲状腺鳞癌患者的临床资料。结果单纯性鳞癌4例,合并甲状腺其它疾病8例。主要临床表现为颈部包块和声嘶。单纯性鳞癌免疫组化甲状腺球蛋白染色阳性3例,阴性1例。12例患者中10例行姑息性切除者于术后1年内死亡,2例行根治性切除者存活时间超过3年。结论原发性甲状腺鳞癌呈高度恶性,可与甲状腺其它良、恶性疾病并存; 要重视对该病的诊断和鉴别诊断,免疫组化甲状腺球蛋白染色可提高确诊率; 根治性手术切除加综合治疗是提高其生存率的关键。
Citation:
李俊,赵永恒,贾卫国,林琦远,龚日祥,朱精强. CLINICAL ANALYSIS IN 12 CASES OF PRIMARY SQUMAOUS CELL CARCINOMA OF THE THYROID. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2002, 9(6): 433-434. doi:
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- 1. Livolsi VA, Merino MJ. Squamous cells in the human thyroid gland [J].Am J Surg pathol, 1978; 2(2)∶133.
- 2. White IL, Talbert WM. Squamous cell carcinoma arising in thyroglossal duct remnant cyst epithelium [J]. Otolaryngol Head Neck Surg, 1982; 90(1)∶ 25.
- 3. Shimaoka K, Tsukada Y. Squamous cell carcinoma and adenosquamous carcinomas originating from the thyroid gland [J]. Cancer, 1980; 46(8)∶1833.
- 4. Simpson WJ, Carruthers J. Squamous cell carcinoma of the thyroid gland [J]. Am J Surg, 1988; 156(1)∶44.
- 5. 韩鑫,杨道科. 13例甲状腺鳞癌治疗体会 [J]. 河南医科大学学报,1995; 30(2)∶226.