• The Department of Nuclear Medicine, Daping Hospital and The Research Institute of Surgery, Thirid Military Medical University, Chongqing 400042;
Gallstone Plasma Bile Gallbladder tissu Motilin Vasoactive intestinal peptide
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Objective  To discuss the relationship between motilin, vasoactive intestinal peptide and the gallstone formation.
Methods  The level of motilin, vasoactive intestinal peptide in plasma, bile and gallbladder tissue of 48 cases of chololithiasis before operation and the first, third, seventh day after cholecystectomy were mesured by radioimmunoassay.
Results  The level of motilin in plasma was markedly increased in patients with chololithiasis before cholecystectomy and the first day after cholecystectomy. The level of motilin, vasoactive intestinal peptide in bile and gallbladder tissue were significantly increased in patients and motilin was positively correlated with vasoactive intestinal peptide in the gallbladder tissue.
Conclusion  Motilin, vasoactive intestinal peptide might affect the gallstone formation by affecting the motility of gallbladder.

Citation： ZHOU WEN,YANG Jinqing,WEN Yayuan,et al.. CHANGES AND ITS SIGNIFICANCE OF MOTILIN， VASOACTIVE INTESTINAL PEPTIDE IN PLASMA， GALLBLADDER TISSUS AND BILE IN PATIENTS WITH GALLSTONE DISEASE. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 2001, 8(3): 171-172下转186. doi: Copy