胃癌中p16基因研究概况_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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刘君 ¹ , 蒲永东 ¹ , 宋少柏 ²

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Citation： 刘君,蒲永东,宋少柏. 胃癌中p16基因研究概况. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1999, 6(3): 190-191. doi: Copy

1.	Deng GR, Lu YY, Chen SM, et al. Actived cHras oncogene with a guanine to thymine transversion at the twelfth codon in a human stomach cancer cell line. Cancer Res, 1987; 47(12)∶3159.
2.	Serrano M, Hannon GJ, Beach D. A new regulatory motif in cellcycle control causing specific inhibition of cyclin D/CDK4. Nature, 1993; 366(16)∶704.
3.	Kamb A, Gruis NA, Feldhaus JW, et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science, 1994; 264∶436.
4.	Nobori T, Miura K, Wu DJ, et al. Deletion of the cyclindependent kinase 4 inhibitor gene in multiple human cancers. Nature, 1994; 368(6472)∶753.
5.	Herman JG, Merlo A, Mao LI, et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrent DNA methylation in all common human cancers. Cancer Res, 1995; 55(20)∶4525.
6.	Merlo A, Herman JG, Mao L, et al. 5’CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancer. Nat Med, 1995; 1(7)∶686.
7.	Igaki H, Sasaki H, Kishi T, et al. Highly frequent homozygous deletion of the p16 gene in esophageal cancer cell lines. Biochem Biophys Res Commun, 1994; 203(2)∶1090.
8.	Akama Y, Yasui W, Kuniyasu H, et al. Genetic status and expression of the cyclindependent kinase inhibitors in human gastric carcinoma cell lines. Jpn J Cancer Res, 1996; 87(8)∶824.
9.	吕有勇，高崇峰，崔建涛等. 胃癌中MTS1/p16基因缺失及表达异常的研究. 中华肿瘤杂志， 1996； 18(3)∶189.
10.	Chen YJ, Chang LG, Shih LS, et al. Frequent deletion of aberrent RNA transcripts of the CDKN2 gene in human gastric adenocarcinoma. Int J Cancer, 1997; 71(3)∶350.
11.	高华，袁媛，王兰等. 抑癌基因p16在胃癌前疾病及胃癌表达的研究. 中华病理学杂志， 1997； 26(3)∶165.
12.	张丹，王继红，姜彦多等. 胃癌中p16基因产物表达的研究. 中华消化杂志， 1997； 17(3)∶178.
13.	Resnitzky D, Gossen M, Bujard H, et al. Acceleration of the G1/S phase transition by expression of cyclin D1 and E with an inducible system. Mol Cell Biol, 1994; 14(3)∶1669.
14.	La Thangue NB. DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated n cellcycle control. Trends Biochem Sci, 1994; 19(3)∶108.
15.	Marx J. New Tumor suppressor may rival p53. Science, 1994; 264∶344.
16.	Marx J. How cell cycle toward cancer. Science, 1994; 263∶319.
17.	Hunter T, Pines J. Cyclins and cancer Ⅱ: cyclin D and CDK inhibitors come of age. Cell, 1994; 79(4)∶573.
18.	Shapiro GI, Edwards CD, Kobzik L, et al. Reciprocal inactivation and p16INK4 expression in primary lung cancers and cell lines. Cancer Res, 1995; 55(3)∶505.
19.	Tam SW, Shay JW, Pagano M. Differential expression and cell cycle regulation of the cyclindependent kinase 4 inhibitor p16INK4. Cancer Res, 1994; 54(22)∶5816.
20.	孙梅，吕有勇. 外源性p16基因表达可抑制人胃癌细胞的恶性增殖. 中华肿瘤杂志， 1997； 19(6)∶410.

1. Deng GR, Lu YY, Chen SM, et al. Actived cHras oncogene with a guanine to thymine transversion at the twelfth codon in a human stomach cancer cell line. Cancer Res, 1987; 47(12)∶3159.
2. Serrano M, Hannon GJ, Beach D. A new regulatory motif in cellcycle control causing specific inhibition of cyclin D/CDK4. Nature, 1993; 366(16)∶704.
3. Kamb A, Gruis NA, Feldhaus JW, et al. A cell cycle regulator potentially involved in genesis of many tumor types. Science, 1994; 264∶436.
4. Nobori T, Miura K, Wu DJ, et al. Deletion of the cyclindependent kinase 4 inhibitor gene in multiple human cancers. Nature, 1994; 368(6472)∶753.
5. Herman JG, Merlo A, Mao LI, et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrent DNA methylation in all common human cancers. Cancer Res, 1995; 55(20)∶4525.
6. Merlo A, Herman JG, Mao L, et al. 5’CpG island methylation is associated with transcriptional silencing of the tumor suppressor p16/CDKN2/MTS1 in human cancer. Nat Med, 1995; 1(7)∶686.
7. Igaki H, Sasaki H, Kishi T, et al. Highly frequent homozygous deletion of the p16 gene in esophageal cancer cell lines. Biochem Biophys Res Commun, 1994; 203(2)∶1090.
8. Akama Y, Yasui W, Kuniyasu H, et al. Genetic status and expression of the cyclindependent kinase inhibitors in human gastric carcinoma cell lines. Jpn J Cancer Res, 1996; 87(8)∶824.
9. 吕有勇，高崇峰，崔建涛等. 胃癌中MTS1/p16基因缺失及表达异常的研究. 中华肿瘤杂志， 1996； 18(3)∶189.
10. Chen YJ, Chang LG, Shih LS, et al. Frequent deletion of aberrent RNA transcripts of the CDKN2 gene in human gastric adenocarcinoma. Int J Cancer, 1997; 71(3)∶350.
11. 高华，袁媛，王兰等. 抑癌基因p16在胃癌前疾病及胃癌表达的研究. 中华病理学杂志， 1997； 26(3)∶165.
12. 张丹，王继红，姜彦多等. 胃癌中p16基因产物表达的研究. 中华消化杂志， 1997； 17(3)∶178.
13. Resnitzky D, Gossen M, Bujard H, et al. Acceleration of the G1/S phase transition by expression of cyclin D1 and E with an inducible system. Mol Cell Biol, 1994; 14(3)∶1669.
14. La Thangue NB. DRTF1/E2F: an expanding family of heterodimeric transcription factors implicated n cellcycle control. Trends Biochem Sci, 1994; 19(3)∶108.
15. Marx J. New Tumor suppressor may rival p53. Science, 1994; 264∶344.
16. Marx J. How cell cycle toward cancer. Science, 1994; 263∶319.
17. Hunter T, Pines J. Cyclins and cancer Ⅱ: cyclin D and CDK inhibitors come of age. Cell, 1994; 79(4)∶573.
18. Shapiro GI, Edwards CD, Kobzik L, et al. Reciprocal inactivation and p16INK4 expression in primary lung cancers and cell lines. Cancer Res, 1995; 55(3)∶505.
19. Tam SW, Shay JW, Pagano M. Differential expression and cell cycle regulation of the cyclindependent kinase 4 inhibitor p16INK4. Cancer Res, 1994; 54(22)∶5816.
20. 孙梅，吕有勇. 外源性p16基因表达可抑制人胃癌细胞的恶性增殖. 中华肿瘤杂志， 1997； 19(6)∶410.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

胃癌中p16基因研究概况

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