THE EFFECT OF NEOSTIGMINE ON COLONIC ANASTOMOTIC HEALING AFTER THE LEFT HEMICOLON OBSTRUCTION：AN EXPERIMENTAL AND CLINICAL STUDY_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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Department of General Surgery, Yijishan Hospital, Wannan Medical College, Wuhu 241001;

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Colonic anastomotic dehiscene; Neostigmine

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In this study, the effect of neostigmine on the healing of colonic anastomoses has been investigated following onestage resection and anastomosis for complete leftsided colomic obstruction.It was found that neostingmine promoted colonic anastomotic healing either experimentally or clinically. Further, the authors discuss the pathogenesis of anastomotic leakage but suggest that neostigmine should be used in the first 5 hours after operation.

Citation： Hu jiqiong,Zhou Guang,Liu Zhongjin,et al.. THE EFFECT OF NEOSTIGMINE ON COLONIC ANASTOMOTIC HEALING AFTER THE LEFT HEMICOLON OBSTRUCTION：AN EXPERIMENTAL AND CLINICAL STUDY. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1998, 5(1): 12-13. doi: Copy

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1. Fraser B, Coxon J, Taylor I,et al. A device to simulate the mechanical component of malignant bowel obstruction. Arch Surg, 1981； 116(2)∶194.
2. Uden P, Blomquist P, Jiborn H,et al. Influence of proximal colostomyon the healing of a left colon anastomosis:an experimental study in the rat. Br J Surg, 1988； 75(4)∶325.
3. 史海安.对结肠一期切除术的几点看法.实用外科杂志，1990；10(3)∶161.
4. 周有生，芦晓明，周颜才.红霉素促进腹部手术后肠蠕动的临床研究.腹部外科杂志， 1996； 9(1)∶25.
5. Jiborn H, Ahonen J, Zederfeldt B,et al. Healing of experimental colonic anastomoses:bursting strength of the colon after left colon resection and anastomosis. Am J Surg, 1978； 136(4)∶587.
6. Tornqvist A, Jiborn H, Zederfeldt B,et al. Anastomotic healing after resection of leftcolon stenosis: effect on collagen metabolism and anastomotic strength. Dis Colon Rectum, 1990； 33(3)∶217.
7. Ravo B, Metwally N, Castera P,et al.The importance of intraluminal anastomotic fecal contact and peritonitis in colonic anastomotic leakages:an experimental study.Dis Colon Rectum, 1988； 31(7)∶868.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

THE EFFECT OF NEOSTIGMINE ON COLONIC ANASTOMOTIC HEALING AFTER THE LEFT HEMICOLON OBSTRUCTION：AN EXPERIMENTAL AND CLINICAL STUDY

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