In order to investigater the effect of nutritional support on nutrients metabolism after liver resection,we researched into the hepatectomy and total parenteral nutrition model in rats.The features of the model were no fasting before surgery,10% glucose subcutaneous injection prior to operation avoiding of blood loss and shortening of the surgical process.The 7-day mortality was markedly decreased.Anesthetized with phenobarbital(25mg/kg) injection in combination of ether inhalation,the rats recovered quickly from anesthesia and developed almost no infection of the respiratory tract after hepatectomy.The rats were supplied parenterally energy of 573kJ/kg and a marked improvement in survival was achieved after liver resection.By applying dual preventive rotation equipment of protective spring and IN-Stopper,nutrient solution could be safely infused.
Citation：
Jia Qianbing,Wu Yantao,Yan Lunan.. RESEARCHES INTO HEPATECTOMY AND TOTAL PARENTERAL NUTRITION IN RATS. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1997, 4(1): 11-12. doi:
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Sitzman JV,Greene PS.Perioperative predictors of morbidity following hepatic resction for neoplasm.Ann Surg,1994,219(1):13.
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Higgins GM,Anderson RM.Experimental pathology of the liver.I.Restoration of the liver of the white rat following partial surgical removal.Arch Pathol,1931;12:186.
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Delany HM,John J,Teh EL,et al.Contrasting effects of identical nutrients given parenterally or enterally after 70% hepatectomy.Am J Surg,1994;167:135.
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| 4. |
Burt ME,Arbit J,Brennam MF,et al.Chronic arterial and venous access in the unrestrained rat.Am J Physiol,1980;238:599.
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- 1. Sitzman JV,Greene PS.Perioperative predictors of morbidity following hepatic resction for neoplasm.Ann Surg,1994,219(1):13.
- 2. Higgins GM,Anderson RM.Experimental pathology of the liver.I.Restoration of the liver of the white rat following partial surgical removal.Arch Pathol,1931;12:186.
- 3. Delany HM,John J,Teh EL,et al.Contrasting effects of identical nutrients given parenterally or enterally after 70% hepatectomy.Am J Surg,1994;167:135.
- 4. Burt ME,Arbit J,Brennam MF,et al.Chronic arterial and venous access in the unrestrained rat.Am J Physiol,1980;238:599.
