COMPARISON OF THERAPEUTIC EFFECTS BETWEEN LIPOFUNDIN AND INTRALIPID IN TOTAL PARENTERAL NURITION_CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

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Department of Surgery, The First Affiliated Hospital of Chongqing Medical University, Division of General Surgery, First Affiliated Hospital, West China University of Medical Science, Chengdu 610041;

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Keywords：

Fat emuision; Parenteral nutrtion; Lipofundin; Lntralipid

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1993年10月至1994年2月对中—长链脂肪乳剂(实验组，n=40)和长链脂肪乳剂(对照组，n=30)在静脉营养中的疗效进行了对比观察。从术后第1天起，除从周围静脉输注必需液体外，每日静滴中—长链或长链脂肪乳剂500～1000ml，连续3～5天。监测项目包括血压、脉搏、呼吸、体温、血红蛋白、白细胞、肝肾功能、血甘油三酯及血胆固醇。结果显示：两组均无全笛反应；在输脂肪乳剂后6小时，两组血甘油三酯含量均明显升高，并于12小时时达峰值，16小时时已明显下降，但对照组明显高于实验组(P lt;0.05)，24小时时仍维持较高水平。由此表明，中—长链肪乳剂较易从血清中清除；中链甘油三酯能快速进入线粒体被氧化供能，不依赖内毒碱的转运，能经肝脏生成更多的酮体，极少再脂化为脂肪贮存起来。

Citation： Shi De,Hu Luoli,Huang Ping,et al.. COMPARISON OF THERAPEUTIC EFFECTS BETWEEN LIPOFUNDIN AND INTRALIPID IN TOTAL PARENTERAL NURITION. CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY, 1994, 1(2): 100-103. doi: Copy

1.	Fan ST, Wang J. Metabolic clearance of a fat emulsion containig medium-chain triglycerides in cirrbotic patients. JPEN, 1992;16:279.
2.	Carpentier BA, Richelle M, Haumont D, et al. New development in fat emulsion.Proceeding Natr Sociery, 1990;49:375.
3.	Wichlayr M, Baldermann H, Rett K, et al. Comparison of metabolic clearance rates of MCT/LCT and LCT emulsions in diabetics, JPEN, 1988;12:68.
4.	杨乃发，蒋朱明.输入不同链长的脂肪乳剂后血中酮的动态观察.中国医学科学院学报，1992；6：424.
5.	Ball MJ, White K.Comparison of medium and long chain riglyceride metabolism in intensive care patients on parenteral nutrition. Intensive Cate Med, 1989;15:250.
6.	Gordon L, Jensen GL, Edward A, et al. Parenteral infusion of long-and medium-chain trilgycerides and reticulo-endothelial system function in man.JPEn, 1990;14:47.
7.	Sedman PC, Ramsden CW, Brenman CW, et al. Pharmacological concentrations of lipid emusions inhibit interleukin-2 dependent lymphocyte responsed in vitro.JPEN, 1990;14:12.
8.	Selman PC, Brenman S, Somer S, et al. Effects of different lipid emulsion on lymphoxyte function during total parenteral nutrition.Br J Surg, 1991;78:1396.
9.	Maiz A, Yamazaki K, Sabrado J, et al. Peotein metacolism during total parenteral nutrition in injured rats using medium chain triglycerides. Metabolism, 1984;33:901.

1. Fan ST, Wang J. Metabolic clearance of a fat emulsion containig medium-chain triglycerides in cirrbotic patients. JPEN, 1992;16:279.
2. Carpentier BA, Richelle M, Haumont D, et al. New development in fat emulsion.Proceeding Natr Sociery, 1990;49:375.
3. Wichlayr M, Baldermann H, Rett K, et al. Comparison of metabolic clearance rates of MCT/LCT and LCT emulsions in diabetics, JPEN, 1988;12:68.
4. 杨乃发，蒋朱明.输入不同链长的脂肪乳剂后血中酮的动态观察.中国医学科学院学报，1992；6：424.
5. Ball MJ, White K.Comparison of medium and long chain riglyceride metabolism in intensive care patients on parenteral nutrition. Intensive Cate Med, 1989;15:250.
6. Gordon L, Jensen GL, Edward A, et al. Parenteral infusion of long-and medium-chain trilgycerides and reticulo-endothelial system function in man.JPEn, 1990;14:47.
7. Sedman PC, Ramsden CW, Brenman CW, et al. Pharmacological concentrations of lipid emusions inhibit interleukin-2 dependent lymphocyte responsed in vitro.JPEN, 1990;14:12.
8. Selman PC, Brenman S, Somer S, et al. Effects of different lipid emulsion on lymphoxyte function during total parenteral nutrition.Br J Surg, 1991;78:1396.
9. Maiz A, Yamazaki K, Sabrado J, et al. Peotein metacolism during total parenteral nutrition in injured rats using medium chain triglycerides. Metabolism, 1984;33:901.

CHINESE JOURNAL OF BASES AND CLINICS IN GENERAL SURGERY

COMPARISON OF THERAPEUTIC EFFECTS BETWEEN LIPOFUNDIN AND INTRALIPID IN TOTAL PARENTERAL NURITION

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