NIE Xiaomeng , BAI Chenguang , SUN Qinying , YAO Xiaopeng
  • Department of Respiratory Medicine, Changhai Hospital, SecondMilitary Medical University. Shanghai, 200433, ChinaCorresponding Author: YAO Xiao-peng, E-mail: yaoxp@ medmail. com. cn;
Sarcomatoid carcinoma; Gefitinib; Literature review
Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables References Cited by

Objective  To investigate the effects of gefitinib in the treatment of sarcomatoid carcinoma.
Methods  Clinical data of a case of sarcomatoid carcinoma was analyzed and related literatures were reviewed.
Results  A patient with sarcomatoid carcinoma was admitted with progressive dry cough,chest pain and dyspnea for 3 months. The patient was diagnosed as lung sarcomatoid carcinoma by thoracoscopy and treated with gefitinib. After 2 weeks treatment, symptoms disappeared and tumor was stable for 4 months. Literatures review suggested that sarcomatoid carcinoma is a rare malignant tumor. Treatment of sarcomatoid carcinoma includes surgery, chemotherapy and radiotherapy, but these methods show little effect in advanced patients. In our case, the patient with sarcomatoid carcinoma in stage Ⅳ was treated by gefitinib and showed favourable effect.
Conclusions  Advanced sarcomatoid carcinoma patients have a short life span and poor life quality. Gefitinib may provide these patients a feasible therapeutic approach.

Citation： NIE Xiaomeng,BAI Chenguang,SUN Qinying,YAO Xiaopeng. Effects of Gefitinib in Treatment of Sarcomatoid Carcinoma of Lung:A Case Report and Literature Review. Chinese Journal of Respiratory and Critical Care Medicine, 2012, 11(2): 172-175. doi: Copy