Objective To evaluate the efficacy and safety of whole lung lavage in the treatment of pulmonary alveolar proteinosis ( PAP) .
Methods Twelve patients who were diagnosed as PAP from September 2008 to October 2011 in Hunan Occupational Disease Hospital were recruited in the study. The changes of dyspnea symptom, lung-function, arterial blood gas, and chest image were compared before and after whole lung lavage treatment. Meanwhile, the safety of lung lavage was evaluated.
Results All patients were relieved from dyspnea. The lung function, hypoxia, hyperventilation, and chest image were all obviously improved. The vital signs in the process of lung lavage were stable without serious complications.
Conclusion Whole lung lavage is an effective and safe treatment for PAP.
Citation： LI Xin,CHEN Ping,XIAO Xiongbin,LUO Guangming,DAI Weirong,LI Ying. Efficacy and Safety of Whole Lung Lavage in Treatment of Pulmonary Alveolar Proteinosis. Chinese Journal of Respiratory and Critical Care Medicine, 2012, 11(4): 391-394. doi: Copy