LIU Yuxue , WANG Xin.
  • Department of Cardiovascular Surgery,Cardiovascular Institute and Fu Wai Cardiovascular Hospital，Chinese Academy of Medical Sciences &;
  • Peking Union Medical College， Beijing 100037，P．R．China;;
Atrial fibrillation; Electrical remodeling; Structural remodeling; Mechanism
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Atrial fibrillation(AF) is the most common disorder of cardiac rhythm. It has a high morbidity, mortality and disability, and serious impact on quality of life of patients. It is demonstrated that atrial remodeling which includes atrial electrical remodeling and structural remodeling,are the central contributors to the development and selfperpetuating of AF. However, The mechanisms that underlie the atrial remodeling process in AF have not yet been completely elucidated. New strategies for the prevention and termination of AF should build on our knowledge of the mechanisms of atrial remodeling. Medication for the reversal of atrial remodeling may be the new target for the treatment of AF. At present, drugs that target atrial remodeling have already obtained fruitful results in the experimental and clinical investigations. Now some recent advancements of this area is reviewed in this article.

Citation： LIU Yuxue,WANG Xin.. Advances of Mechanism of the Atrial Remodeling in Atrial Fibrillation. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2009, 16(3): 218-222. doi: Copy