• Department of Thoracic and Cardiovascular Surgery, Nanjing First Hospital Affiliated to Nanjing Medical University, Nanjing Heart Institute,Nanjing 210006, P.R. China;
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Objective To investigate the risk factors of
grafts stenosis following coronary artery bypass grafting (CABG), in an effort to benefit the prevention and treatment of graft stenosis after CABG. Methods The clinic data of 197 patients who underwent CABG and received selective angiography between January 1999 and December 2007 were retrospectively analyzed and all patients were subdivided into stenosis group (n=87) and normal group(n=110). Statistic analysis of χ2 test, ttest and multiple logistic regressions were used to find out the risk factor. Results It was demonstrated by angiography that there was graft stenosis after CABG in 87 patients involved 321 stomas (305 in the distal and 16 in the proximal). Univariate analysis revealed that diabetes mellitus,dyslipidemia, distal anastomoses in right coronary artery (RCA) territory, <70% stenosis in target coronary artery, <1.5 mm in diameter in target artery, saphenous vein grafts(SVG) and offpump CABG were significantly related to stenosis of grafts following CABG, and logistic multivariate regression analysis showed that diabetes mellitus(OR=3.654), dyslipidemia(OR=2.625), distal anastomoses in RCA(OR=1.694), <70% stenosis in target coronary artery(OR=1.763), <1.5 mm in diameter in target artery (OR=1.337)and utilization of SVG (OR=1.652) were independent risk factors of graft stenosis. Conclusion Diabetes mellitus,dyslipidemia, distal anastomoses in RCA, <70% stenosis in target coronary artery, <1.5 mm in diameter in target artery and utilization of SVG are the risk factors of graft stenosis following CABG.

Citation: CHEN Xujun,CHEN Xin,SHI Kaihu,et al .. Analysis of the Risk Factors of Graft Stenosis Following Coronary Artery Bypass Grafting. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2008, 15(6): 418-422. doi: Copy