YANG Jun min , SONG Ling , ZHANG Bao ren , et al.
  • Department of Cardiac and Thoracic Surgery;;
  • Southwest Hospital;;
  • The Third Military Medical University;;
  • Chongqing 400038;;
  • P.R.China;;
Interferon Rheumatic heart disease Transforming growth factor β
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Objective\ To understand the effects of serum of patients with rheumatic heart disease and γ interferon on collagen synthesis by valvular fibroblast cultured in vitro, so as to investigate the possible role of transforming growth factor β in genesis of valvular fibrosis and the possibility of γ interferon used to prevent valvular fibrosis in patient with rheumatic heart disease.\ Methods\ Mitral and aortic valve fibroblasts from 5 patients with rheumatic heart disease were cultured in vitro, the cultured ...

Citation： YANG Jun min,SONG Ling,ZHANG Bao ren,et al.. Effects of Autologous Serum and γ-Interferon on Collagen Synthesis by Valvular Fibroblast in Patient with Rheumatic Heart Disease. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2000, 7(3): 175-177. doi: Copy