YUAN Biao , ZHU Lang biao , WANG Dong qing , et al.
  • Department of Cardiovascular Surgery;;
  • General Hospital of PLA;;
  • Beijing 100853;;
  • P.R.China;;
Creatine phosphate Isolated rat heart Energy metabolism Mitochondria
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Objective\ To study the mechanism of myocardial protection of exogenous creatine phosphate (CP) against ischemia reperfused injury in modified isolated perfused working rat heart model.\ Methods\ Seventy two rats were divided into five groups.The rat hearts of five groups undergone Langendorff perfused were arrested and made totally ischemic for 40 minutes at 37℃ and reperfused for 20 minutes. St.Thomas cardioplegic solution wasn’t used in group A;It was used immediately after ischemia in group B and grou...

Citation： YUAN Biao,ZHU Lang biao,WANG Dong qing,et al.. Effect of Exogenous Creatine Phosphate on Energy Metabolism and Mitochondrial Function in Isolated Rat Hearts. Chinese Journal of Clinical Thoracic and Cardiovascular Surgery, 2000, 7(3): 178-182. doi: Copy