WANG Yaojun , CEN Ying , LI Zhengyong , et al.
  • Department of Plastic and Burns Surgery, West China Hospital，Sichuan University, Chengdu Sichuan，610041，P. R. China;
Malignant melanoma; Clinical stage; Operati on; Adjunctive therapy; RoferonA
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Objective To observe the effects of operation with large-dose of RoferonA for cutaneous malignant melanoma. Methods From January 1998 to December 2005, thirtythree patients with cutaneous malignant melanoma were treated. There were 20 males and 13 females, aging 17-79 years. The disease course was 2 months to 7 years. In 33 patients, nine patients identified as clinical-stage Ⅰ received singly enlargedresection to the primary lesion and performed split-thickness skin graft dermoplasty or adjacent skin flap repair; twenty-three patients identified as clinicalstage Ⅱ received enlargedresection to the primarylesion and performed proximal lymphaden scavenge as well as received split-thickness skin graft dermoplasty; and one patient identified as clinical-stage Ⅲ received palliative resection to the primary lesion. All patients received large dose of Roferon-A after operation. Results There are no recidivation in the 9 patients of clinicalstage Ⅰ. There are 1 recidivation and 1 quit in all the 23 patientsof clinicalstage Ⅱ. One patient of clinicalstage Ⅲ died after 18 months of operation. Conclusion The operation combined with large-dose of RoferonA after operation was a more effective way to treat cutaneous malignant melanoma.

Citation： WANG Yaojun,CEN Ying,LI Zhengyong,et al.. THERAPEUTIC RESULT OF OPERATION COMBINED WITH LARGEDOSE OF ROFERONA FOR CUTANEOUS MALIGNANT MELANOMA. Chinese Journal of Reparative and Reconstructive Surgery, 2007, 21(1): 37-39. doi: Copy