ZHAO Huan , DING Yi , YANG He , et al.
  • West China Collage of Stomatology, Sichuan University, Chengdu Sichuan，610041, P.R.China.;
Polypeptide growth factor; Periodontal ligam ent cell; Periodontal tissue regeneration
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Objective To evaluate the effects of the polypeptide growth factors on the periodontal ligament cell(PDLC) based on a comprehensive review onthe literature concerned. Methods The recent literature related to the effects of the polypeptide growth factors on the PDLC were extensivelyand comprehensively reviewed and a corresponding evaluation was made. Results The proliferation and the multidirectional differentiation of thePDLC were found to be the basis for the regeneration of the periodontal tissues. The effects of the polypeptide growth factors on the function of the PDLC became a hot issue of the research on the regeneration of the periodontal tissues. The polypeptide growth factors were found to play an important role in the migration, growth, proliferation, differentiation, and synthesis of protein and matrixof the PDLC. Conclusion The polypeptide growth factors can beused in the periodontal regeneration treatment, but a further research is stillrequired to improve this kind of treatment.

Citation： ZHAO Huan,DING Yi,YANG He,et al.. EFFECTS OF GROWTH FACTORS ON PERIODONTAL LIGAMENT CELLS. Chinese Journal of Reparative and Reconstructive Surgery, 2007, 21(2): 171-174. doi: Copy