• Department of Tissue Engineering, China Medical University, Shenyang Liaoning, 110001, P. R . China;
Heterogeneous blood vessel; Scaffold; Transplantation
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Objective To establish a scaffold model from heterogeneoussmall blood vessels. Methods Caudal arteries from 34 Wistar rats( average length 12.08±1.69 cm) were made into acellular blood vessel scaffolds. Some scaffoldswere observed by electron microscope, and others were transplanted to the cut ends of ear central arteries of male Japanese big ear white rabbits. Results Average external diameter was 0.74±0.08 mm in proximal, and 0.55±0.08 mm in distal end of rat caudal arteries. The small blood vessel scaffolds had shin wall whichwas white and soft, composed of fibrous tissues without cells. On the intima surface the fibrous tissues were arrayed densely in a grid-like pattern. After transplantation, the blood flow was reserved, and kept flowing freely in 24 hours. The pulsation of the transplanted artery was accessible and no blood leakage wasfound.Conclusion The natural scaffolds are composed of fibrous tissues, and can sustain the artery pulse pressure for 24 hours. It is better to suture the blood vessels by sleeve anastomosis. 

Citation： CHEN Huayong,BAI Shuling,WANG Jun,et al.. CONSTRUCTION OF THE SCAFFOLD MODEL FROM HETEROGENEOUS SMALL BLOOD VESSELS. Chinese Journal of Reparative and Reconstructive Surgery, 2005, 19(5): 392-394. doi: Copy