• nstitute of Trauma and Orthopedics of PLA;;
  • Fourth Military Medical University. Xi an Shaanxi;;
  • P. R. China 710032;;
Tissue engineering bone; Alginate; Xenograft
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Objective To investigate bio characteristics of bone stromal cells (MSC) in different concentrations of alginate combined with xenograft. Methods The configuration and secretion of MSC in different concentrations of alginate combined with xenograft were observed by scanning electron microscope and inverted microscope. Results When the concentration of alginate was 0.25% or 1%, alginate was equally combined in xenograft, 4% and 8% only on the surface of xenograft. After cultured for 4 days, alginate of 0.25# came off from xenograft. But alginate of 1% was equally combined in xenograft with cell secreting well in alginate. The growth of cells in alginate of 4% was restricted and no cell was seen in alginate of 8%. Conclusion Alginate of 1% is suitable fro constructing carrier of tissue engineering bone.

Citation： SUN Lei,MENG Guo lin,DOU Yu sheng,et al. I. CONSTRUCTION OF CARRIER FOR BONE TISSUE ENGINEERING WITH DIFFERENT CONCENTRATIONS OF ALGINATE CONBINED WITH XENOGRAFT. Chinese Journal of Reparative and Reconstructive Surgery, 2003, 17(2): 140-142. doi: Copy