OBJECTIVE: To prepare chitosan-gelatin/hydroxyapatite (CS-Gel/HA) composite scaffolds, and to investigate the influence of components and preparing conditions to their micromorphology. METHODS: The CS-Gel/HA composite scaffolds were prepared by phase-separation method. Micromorphology and porosity were detected by using scanning electron microscope and liquid displacement method respectively. RESULTS: Porous CS-Gel/HA composite scaffolds could be prepared by phase-separation method, and their density and porosity could be controlled by adjusting components and quenching temperature. CONCLUSION: The study suggests the feasibility of using CS-Gel/HA composite scaffolds for the transplantation of autogenous osteoblasts to regenerate bone tissue.
Citation： ZHAO Feng,YIN Yu ji,SONG Xue feng,et al.. STUDY ON CHITOSAN-GELATIN/HYDROXYAPATITE COMPOSITE SCAFFOLDS--PREPARATION AND MORPHOLOGY. Chinese Journal of Reparative and Reconstructive Surgery, 2001, 15(5): 276-279. doi: Copy