• Department of Urological Surgery;;
  • the First University Hospital;;
  • West China University of Medical Sciences. Chengdu Sichuan;;
  • P. R. China 610041;;
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OBJECTIVE: To investigate the effect of vasostomy on apoptosis in the male rat spermatogenic cells after vasoligation. METHODS: Model of vasoligation and vasostomy in male rat was established, and then terminal deoxynucleotidyl transferase-mediated dUTP nick labelling technique to detect the apoptosis of spermatogenic cells at 4, 8, 12, 16 weeks after vasostomy. RESULTS: The number of apoptotic cells in vasostomy group was significantly lower than that of vasoligation group since 8 weeks after vasostomy(P  lt; 0.05). The number of apoptotic cells in 8 and 12 weeks after vasostomy were significantly higher than that in prevasoligation(P  lt; 0.05). 16 weeks after vasostomy, the number of apoptotic cells restored to the level same as that in prevasoligation stage. CONCLUSION: Vasostomy can reverse the apoptosis of spermatogenic cells due to vasoligation.

Citation: DONG Qiang,YANG Yuru,ZHANG Weidong,et al.. STUDY OF APOPTOSIS IN THE MALE RAT SPERMATOGENIC CELLS AFTER VASOSTOMY. Chinese Journal of Reparative and Reconstructive Surgery, 2000, 14(5): 298-298. doi: Copy