OBJECTIVE To observe the effects of basic fibroblast growth factor(bFGF) on the healing of cutaneous chronic wounds. METHODS Twenty-eight cases with thirty-three wounds from trauma, diabetes, pressure and radiation injuries were locally treated with bFGF in a dosage of 150 U/cm2 wounds. The healing time of wounds was used to evaluate the treatment results. RESULTS The healing time in all of chronic wounds were accelerated. All wounds from trauma, diabetes and pressure were healed within 4 weeks and another 2 wounds from radiation injuries were healed over 4 weeks. The healing rate within 4 weeks was 93.9%. CONCLUSION The results indicate that bFGF can be used as a promoter to accelerate the healing of chronic wounds in clinic.
Citation： FU Xiao bing,GUO Zhen rong,SHENG Zhi yong.. EFFECTS OF BASIC FIBROBLAST GROWTH FACTOR ON THE HEALING OF CUTANEOUS CHRONIC WOUNDS. Chinese Journal of Reparative and Reconstructive Surgery, 1999, 13(5): 270-272. doi: Copy