• Orthopedic Surgery Department;;
  • Zhujiang Hospital of the First Military Medical University. Guangzhou Guangdong;;
  • P.R.China 510282;;
Biological membrane; Chitosan; Tendon
Export PDF Favorites Scan Get Citation

Abstract Full text Figures/Tables References Cited by

OBJECTIVE: To investigate the effects of chitosan membrane on tendon adhesion and healing and obtain experimental data for clinical use in preventing postoperative tendon adhesion. METHODS: The long flexor tendon of 55 adult legborn hens were cut and sutured encapsulated by chitosan membrane. Movement and anti-tension capability of tendon were assessed at 2, 4, 6, 8 and 10 weeks after operation by SWD-10 type tendon stretcher. Tendon healing and adhesion were observed with light microscope. RESULTS: Tendon healing could be effected by chitosan membrane within 4 weeks, and tendon anti-tension strength was increased after 4 weeks. CONCLUSION: Chitiosan membrane possesses the following characteristics: no side effects, good permeability, resolvable, absorbable and selective inhibition the growth of fibroblast. It is a desirable biological material to prevent tendon adhesion.

Citation： ZHANG Hui,SHENG Zhi jian,HOU Chun lin.. EFFECT OF CHITOSAN MEMBRANE ON TENDON ADHESION AND HEALING. Chinese Journal of Reparative and Reconstructive Surgery, 1999, 13(6): 382-385. doi: Copy