Wu Boyi 1 , Zhu Jiakai 2 , Zhou Xia otian. 2
  • Department of Microsurgery, First Clinical College of Medicine, Sun Yatsen University of Medical Sciences, Guanzhou. 510260.;
Schwann’s cell; Neuron; Neurotrophic factor; Regeneration of periphral nerve.
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Schwanns cells were obtained from the distal end of the sciatic nerve following Wallerian degeneration of SD rats. These cells were cultured with the anteriorhorn neuron of spinal cord of 14dayold SD rat fetus. The two kinds of cells were separated by a slice. Through the microscope, the dendrites and the morphology changes at the 24th, 48th, 72th, and 96 th hour after culture were observed. It was demonstrated that the Schwanns cells played the role of maintaining the survival of neuron and promoting the growth of dendrites. It was said that the Schwanns cells could secrete neurotrophic factor which made the body enlarged and caused the dendrites enlonged to several times of the body.

Citation： Wu Boyi,Zhu Jiakai,Zhou Xia otian.. THE NEUROTROPHIC EFFECTS OF CULTURING SCHWANNS CELLS ON ANTERIOR HORN NEURON OF SPINAL CORD. Chinese Journal of Reparative and Reconstructive Surgery, 1995, 9(4): 226-228. doi: Copy